Biology and Marine Biology

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Maria Christine White, Arthur R. Frampton Jr. Downregulation of the toll-like receptor 4 pathway

contributes to enhanced killing of human glioma cells by equine herpesvirus type 1. Thirteenth

Southeastern Regional Virology Conference, Atlanta, GA, April 25-27, 2014.

Stephanie E. Johnstone and Arthur R. Frampton Jr. Infection of equine endothelial cells with non-

neurovirulent equine herpesvirus-1 strain KyA elicits greater down regulation of inflammatory

cytokines CCL3, IL8, TGF-2β and CXCL3 compared to neurologic strain OHIO 2003. North

Carolina American Society for Microbiology 2014 Meeting, Appalachian State University,

September 27, 2014.

Invited talks:

Equus caballus MHC class I is an entry receptor for equine herpesvirus type 1 (EHV-1). East Carolina

University School of Medicine, Department of Microbiology and Immunology. November 16, 2010.

Equus caballus MHC class I is an entry receptor for equine herpesvirus type 1 (EHV-1). University

of Kentucky, Department of Veterinary Science, Gluck Equine research Center. January 18, 2011.

Equus caballus MHC class I is an entry receptor for equine herpesvirus type 1 (EHV-1). The Third

Havemeyer EHV-1 Workshop at the Home Ranch, Steamboat Springs, September 18-23, 2011.

Research Grants:

Funded

Grayson Jockey Club Research Foundation. Cell signaling/receptor molecules for EHV-1 infection.

$77,578. 4/1/09-4/1/12.

P.I. Arthur R. Frampton Jr.

North Carolina Horse Council. Isolation and characterization of novel anti-EHV-1 compounds.

$6,000.

8/18/09-8/17/10.

P.I. Arthur R. Frampton Jr.

Friends of UNCW. Investigation of equine herpesvirus 1 (EHV-1) as a novel therapeutic for the

treatment of human glioblastoma brain tumors. $830.26. 7/01/09-01/31/10

P.I. Arthur R. Frampton Jr.

Friends of UNCW. To test the feasibility of using equine herpesvirus type 1 (EHV-1) as a gene

therapy vector for the treatment of cystic fibrosis (CF). $1,250. 7/01/10-01/31/11

P.I. Arthur R. Frampton Jr.

Summer research/curriculum development initiative. 2010. $3,500

P.I. Arthur R. Frampton Jr.

North Carolina Biotechnology Center. Institutional Development Grants Program. Roche Applied

Science (RAS) GS junior system for high throughput DNA sequence core facility at the Center

for Marine Science, University of North Carolina Wilmington. 2010. $114,200.