Textbook of Personalized Medicine - Second Edition [2015]

365 drive various human cancers and will open up the possibility of personalized thera- pies targeted to the molecular pathology ...

366 carcinoma), and ovarian (serous cystadenocarcinoma). Together, these cancers account for more than 258,480 cancer cases each ...

367 physicians and scientists can compare patients’ tissues with digitally archived cancerous tissues for which genomic and prot ...

368 number and sequence data also holds promise for determining whether particular point mutations have a functional effect, the ...

369 therapies; scientifi c interest; and the ability to obtain enough high-quality samples to conduct a large-scale project. To ...

370 Use knowledge from genome-wide association studies and chromosomal instability to predict the progression from benign to ma ...

371 References Acharya CR, Hsu DS, Anders CK, et al. Gene expression signatures, clinicopathological features, and individualize ...

372 Bristow RE, Smith A, Zhang Z, et al. Ovarian malignancy risk stratifi cation of the adnexal mass using a multivariate index ...

373 Davies C, Pan H, Godwin J, et al. Long-term effects of continuing adjuvant tamoxifen to 10 years versus stopping at 5 years ...

374 Fogli S, Caraglia M. Genotype-based therapeutic approach for colorectal cancer: state of the art and future perspectives. Ex ...

375 Hoskins JM, Goldberg RM, Qu P, et al. UGT1A1*28 genotype and irinotecan-induced neutrope- nia: dose matters. J Natl Cancer I ...

376 Kishiki T, Ohnishi H, Masaki T, et al. Overexpression of MET is a new predictive marker for anti- EGFR therapy in metastatic ...

377 Lorenzi PL, Reinhold WC, Rudelius M, et al. Asparagine synthetase as a causal, predictive bio- marker for L-asparaginase act ...

378 Pallud J, Taillandier L, Capelle L, et al. Quantitative morphological MRI follow-up of low-grade glioma: a plead for systema ...

379 Rhodes DR, Ateeq B, Cao Q, et al. AGTR1 overexpression defi nes a subset of breast cancer and con- fers sensitivity to losar ...

380 Sjoblom T, Jones S, Wood LD, et al. The consensus coding sequences of human breast and colorec- tal cancers. Science. 2006;3 ...

381 Torres-Roca JF. A molecular assay of tumor radiosensitivity: a roadmap towards biology-based personalized radiation therapy. ...

K.K. Jain, Textbook of Personalized Medicine, DOI 10.1007/978-1-4939-2553-7_11, 383 © Springer Science+Business Media New York 2 ...

384 Results show that VLU infections are polymicrobial with no single bacterium colonizing the wounds. The most ubiquitous and p ...

385 predictive model based on a set of signifi cant SNPs and indels showed a high degree of accuracy in predicting an isolate’s ...