701Opportunities and Challenges of Personalized Medicine
Prospects and Limitations of Genetic Testing
Genotyping will be for twenty-fi rst century medicine what the X-rays were for
twentieth century clinical practice. Currently there are some reservations about the
value of genetic testing in prediction of disease as there are multiple factors involved.
It is currently being debated if it is worthwhile to continue with the multi-million
dollar genomewide studies or to decode the entire genomes of individual patients.
Although genomewide association studies have worked better and faster than
expected, they have not explained as much of the genetic component of many
2005-2010Medicine in
beginning of 21st
centuryEvolving medicinePersonalized medicine 2010-20152000-2005
Molecular diagnosticsGenetic screening
PharmacoproteomicsPharmacogeneticsPresymptomatic treatment
Integrated healthcarePharmacogenomicsBioinformaticsAutomated systemsEmpirical treatmentsRational therapies© Jain PharmaBiotechFig. 24.1 Evolution of personalized medicine as a market driver
Opportunities and Challenges of Personalized Medicine