Science - USA (2021-12-24)

(Antfer) #1

1634 24 DECEMBER 2021¥VOL 374 ISSUE 6575 science.orgSCIENCE


Fig. 1. Profiles of gut microbiota in patients with melanoma and associa-
tions with outcomes on therapy.(A) Schema of study design. (B) Box plots
comparing the relative abundance of anti–PD-1 response–associated taxa from


Gopalakrishnanet al.( 4 ) with a newly recruited cohort (n= 132) of anti–PD-1–
treated patients (P= 0.036 andP= 0.018, respectively, for Ruminococcaceae
andFaecalibacteriumby Wilcoxon rank sum test). Patients included in the prior

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