V. Summary
Sepsis continues to be a diagnostic and a therapeutic challenge in infants
and children. It remains a leading cause of morbidity, despite our recent
advances in therapy. In those at risk for, or with an already established infection,
early intervention provides the best chance of recovery. A high degree of
suspicion and attention to initially subtle changes in physiology allows us to
provide therapy before progression to physiologic instability. Timely therapy
not only minimizes co-morbidities, but it significantly shortens the time in the ICU
and allows for best long-term outcomes.
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