Chapters
- Introduction
- Special Cases
3 7. Interaction and
Confounding Assessment
- Additional Modeling
Strategy Issues
This presentation is now complete. The reader
may wish to review the detailed summary and
to try the practice exercises and test that
follow.
The next chapter considers additional issues
about modeling strategy, including how to
address more than one exposure variable,
screening variables, collinearity, multiple test-
ing, and influential observations.
SUMMARY (continued)
Interaction present: compare tables
of odds ratios and confidence
intervals (subjective)
Interaction: Safe (for validity) to
keep allVs in model
However, if there is interaction, the assess-
ment of confounding is much more subjective
because it typically requires the comparison
of tables of odds ratio values. Similarly, asses-
sing precision requires comparison of tables
of confidence intervals.
Consequently, if there is interaction, it is typi-
cally safe for ensuring validity to keep all
potential confounders in the model, even
those that are candidates to be deleted as
possible nonconfounders.
232 7. Modeling Strategy for Assessing Interaction and Confounding