Logistic Regression: A Self-learning Text, Third Edition (Statistics in the Health Sciences)

(vip2019) #1

Model for three categories, one
predictor (X 1 = AGEGP):


ln
PðD¼ 1 jX 1 Þ
PðD¼ 0 jX 1 Þ




¼a 1 þb 11 X 1

ln

PðD¼ 2 jX 1 Þ
PðD¼ 0 jX 1 Þ




¼a 2 þb 21 X 1

2 vs. 0

1 vs. 0

a 1 b 11


a 2 b 21


III. Odds Ratio with Three
Categories


^a 1 ^a 2
b^ 11 b^ 21

)


Estimates obtained
as in SLR

Special case for one predictor
whereX 1 ¼1orX 1 ¼ 0


Because our example has three outcome cate-
gories and one predictor (i.e., AGEGP), our
polytomous model requires two regression
expressions. One expression gives the log of
the probability that the outcome is in category
1 divided by the probability that the outcome is
in category 0, which equalsa 1 plusb 11 timesX 1.

We are alsosimultaneouslymodeling the log of
the probability that the outcome is in category
2 divided by the probability that the outcome is
in category 0, which equalsa 2 plusb 21 timesX 1.

Both the alpha and beta terms have a subscript
to indicate which comparison is being made
(i.e., category 1 vs. 0 or category 2 vs. 0).

Once a polytomous logistic regression model
has been fit and the parameters (intercepts
and beta coefficients) have been estimated,
we can then calculate estimates of the disease–
exposure association in a similar manner to the
methods used in standard logistic regression
(SLR).

Consider the special case in which the only
independent variable is the exposure variable
and the exposure is coded 0 and 1. To assess
the effect of the exposure on the outcome, we
compareX 1 ¼1toX 1 ¼0.

Presentation: III. Odds Ratio with Three Categories 437
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