Logistic Regression: A Self-learning Text, Third Edition (Statistics in the Health Sciences)

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General case for one predictor


ORg¼expbg 1 X** 1 X* 1

hi
;where
g¼ 1 ; 2

Computer output for polytomous
model:
Is output listed in ascending or
descending order?


The special case of a dichotomous predictor
can be generalized to include categorical or
continuous predictors. To compare any two
levels (X 1 ¼X** 1 vs.X 1 ¼X* 1 ) of a predictor, the
odds ratio formula is e to the bg 1 times
(X** 1 X* 1 ), wheregdefines the category of the
disease variable (1 or 2) being compared with
the reference category (0).

The output generated by a computer package
for polytomous logistic regression includes
alphas and betas for the log odds terms being
modeled. Packages vary in the presentation of
output, and the coding of the variables must be
considered to correctly read and interpret the
computer output for a given package. For
example, in SAS, ifD¼0 is designated as the
reference category, the output is listed in des-
cending order (see Appendix). This means that
the listing of parameters pertaining to the
comparison with categoryD¼2 precedes the
listing of parameters pertaining to the com-
parison with categoryD¼1, as shown on the
left.

The results for the polytomous model examin-
ing histological subtype and age are presented
on the left. The results were obtained from
running PROC LOGISTIC in SAS. See the
Computer Appendix for computer coding.

There are two sets of parameter estimates. The
output is listed in descending order, with
a 2 labeled as Intercept 1 anda 1 labeled as inter-
cept 2. IfD¼2 had been designated as the
reference category, the output would have
been in ascending order.

EXAMPLE
SAS
Reference category:D¼ 0
Parameters forD¼2 comparison
precedeD¼1 comparison.

Variable Estimate symbol
Intercept 1 ^a 2
Intercept 2 ^a 1
X 1 ^b 21
X 1 ^b 11

EXAMPLE
Variable Estimate S.E. Symbol
Intercept 1 1.4534 0.2618 ^a 2
Intercept 2 1.9459 0.3223 ^a 1
AGEGP 0.4256 0.3215 ^b 21
AGEGP 0.7809 0.3775 ^b 11

Presentation: III. Odds Ratio with Three Categories 439
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