Science - USA (2022-02-04)

IMAGE: NASA’S GODDARD SPACE FLIGHT CENTER

NEWS

IN BRIEF

474 News at a glance

IN DEPTH

478 Imminent merger of giant

black holes predicted

Never-before-seen event could spark cosmic

fireworks—if it is not a mirage By D. Clery

479 Indonesia’s utopian new capital may

not be as green as it looks

Moving the government to Borneo could

speed deforestation By D. Normile

PODCAST

480 New Omicron begins to take over,

despite late start

BA.2 strain may extend latest surge,

but its overall impact remains unclear

By M. Wadman

482 Massive wolf kill disrupts long-

running Yellowstone park study

Hunters kill more than 500 wolves in

surrounding states B y V. M o r e l l

483 Computer scan uncovers

100,000 new viruses

Clues to future outbreaks may be

hidden in existing genomic databases

By E. Pennisi

In this visualization, giant black holes are on the cusp of merging. A team of astronomers has predicted an imminent merger in a distant galaxy.

INSIGHTS

PERSPECTIVES

490 Chasing after methane’s

ultra-emitters

Leaks from oil and gas companies contribute

substantially to global warming B y F. Vo g e l

REPORT p. 557

491 Tethering gene regulation to

chromatin organization

A two-tiered system of chromatin structure

ensures robust gene expression

By M. Gaskill and M. Harrison

REPORT p. 566

493 When viruses become more virulent

Natural selection favors virulence when it is

coupled with increased viral transmission

By J. O. Wertheim

RESEARCH ARTICLE p. 540

494 The adenine methylation debate

N^6 -methyl-2′-deoxyadenosine (6mA) is less

prevalent in metazoan DNA than thought

By K. Boulias and E. L. Greer

RESEARCH ARTICLE p. 515

495 An adaptive device for

AI neural networks

The perovskite nickelate can

transform among four different

electronic components

By R. A. John

RESEARCH ARTICLE p. 533

497 Lethal mutagenesis as an

antiviral strategy

Lethal mutagenesis of RNA viruses

is a viable antiviral strategy but

has unknown risks

By R. Swanstrom and R. F. Schinazi

499 Robert H. Grubbs

(1942–2021)

Brilliant organic chemist

and inspiring mentor By M. Sanford

POLICY FORUM

500 How NFTs could transform

health information exchange

Can patients regain control

over their health information?

By K. Kostick-Quenet et al.

BOOKS E T A L.

503 From dualism to deism

A philosopher comes full circle

By J. Zerilli

504 Imagining Rosalind Franklin

The crystallographer’s story

comes alive in a work of

historical fiction By K. Langin

CONTENTS

4 FEBRUARY 2022

VOLUME 375 • ISSUE 6580

FEATURES

484 Failing the test

DNA barcoding brought botanist

Steven Newmaster scientific fame and

entrepreneurial success. Was it all based on

fraud? By C. Piller

SCIENCE science.org 4 FEBRUARY 2022 • VOL 375 ISSUE 6580 471

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