Science - USA (2022-02-11)

SCIENCE science.org 11 FEBRUARY 2022 • VOL 375 ISSUE 6581 589

PHOTO: XAVIER MASCAREÑAS

RESEARCH

IN BRIEF

625 From Science and other journals

RESEARCH ARTICLES

628 Cell biology

p53 directs leader cell behavior, migration,

and clearance during epithelial repair

K. Kozyrska et al.

RESEARCH ARTICLE SUMMARY; FOR FULL TEXT:

DOI.ORG/10.1126/SCIENCE.ABL

PERSPECTIVE p. 619

629 Immunology

CD97 promotes spleen dendritic

cell homeostasis through the

mechanosensing of red blood cells

D. Liu et al.

RESEARCH ARTICLE SUMMARY; FOR FULL TEXT:

DOI.ORG/10.1126/SCIENCE.ABI

630 Immunology

Marginal zone B cells acquire dendritic

cell functions by trogocytosis

P. S c h r i e k et al.

RESEARCH ARTICLE SUMMARY; FOR FULL TEXT:

DOI.ORG/10.1126/SCIENCE.ABF

631 Cell biology

Mechanism of spindle pole organization

and instability in human oocytes C. So et al.

RESEARCH ARTICLE SUMMARY; FOR FULL TEXT:

DOI.ORG/10.1126/SCIENCE.ABJ

632 Neuroscience

Geometry of sequence working memory in

macaque prefrontal cortex Y. X i e et al.

639 Biomedicine

An autonomously swimming biohybrid fish

designed with human cardiac biophysics

K. Y. Lee et al.

REPORTS

647 Materials science

A damage-tolerant, dual-scale, single-

crystalline microlattice in the knobby starfish,

Protoreaster nodosus T. Yang et al.

PERSPECTIVE p. 615

653 Piezoelectrics

Induced giant piezoelectricity in

centrosymmetric oxides D.-S. Park et al.

PERSPECTIVE p. 618

658 Organic chemistry

Remote steric control for undirected

meta-selective C–H activation of arenes

B. Ramadoss et al.

663 Y chromosome origins

Y recombination arrest and degeneration

in the absence of sexual dimorphism

T. Lenormand and D. Roze

PERSPECTIVE p. 616

667 Coronavirus

COVID mortality in India: National

survey data and health facility deaths

P. J h a et al.

671 Aging

Caloric restriction in humans

reveals immunometabolic regulators

of health span O. Spadaro et al.

PERSPECTIVE p. 620

678 Coronavirus

Neutralization of SARS-CoV-2 Omicron

by BNT162b2 mRNA vaccine–elicited

human sera A. Muik et al.

681 Spatial epigenomics

Spatial-CUT&Tag: Spatially

resolved chromatin modification

profiling at the cellular level

Y. Deng et al.

ON THE COVER

Artificially colored scanning electron

micrograph of a knobby starfish

(Protoreaster nodosus) skeletal element

with small calcite crystals grown on its

surface. This overgrowth experiment

demonstrates this biomineralized structure’s

two single-crystalline components—a

micrometer-scale periodic lattice and the

underlying atomic-scale calcite—that are

aligned by their crystal

symmetry. This

lightweight dual-scale

structure exhibits high

mechanical efficiency

and damage tolerance

for enhanced protection.

See pages 615 and 647.

Image: Ling Li/Virginia Tech

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604

DEPARTMENTS

591 Editorial

The lessons of Lander

By H. Holden Thorp

690 Working Life

Following my curiosity

By Alvina G. Lai