The Essentials of Biostatistics for Physicians, Nurses, and Clinicians

(Ann) #1
70 CHAPTER 5 Estimating Means and Proportions


  1. If a random sample of size n is taken from a population with a distribution
    with mean μ and standard deviation σ , what is the standard deviation (or
    standard error) of the sample mean equal to?

  2. Suppose you want to construct a confi dence interval for the mean of a
    single population based on a random sample of size n from a normal
    distribution. How does a 95% confi dence interval differ if the variance is
    known versus when the variance is unknown?

  3. Describe the bootstrap principle.

  4. Explain how the percentile method bootstrap confi dence interval for a
    parameter is obtained.

  5. Suppose we randomly select 25 students who are enrolled in a biostatistics
    course and their heart rates are measured at rest. The sample mean is 66.9
    and the sample standard deviation is S = 9.02. Assume the sample comes
    from a normal distribution and the standard deviation is unknown.
    Calculate a 95% two - sided confi dence interval for the mean.

  6. How would you compute a one - sided 95% confi dence interval of the form
    ( − ∞ , a] based on the data in exercise 9? Why would you use a one - sided
    confi dence interval?

  7. The mean weight of 100 men in a particular heart study is 61 kg, with a
    standard deviation of 7.9 kg. Construct a 95% confi dence interval for the
    mean.


Table 5.2
Plasma Glucose Levels for Ten Diabetic
Patients
Plasma glucose (mmol/L)
Patient Before After Difference
01 4.64 5.44 0.80
02 4.95 10.01 5.06
03 5.11 8.43 3.22
04 5.21 6.65 1.44
05 5.30 10.77 5.47
06 6.24 5.69 − 0.55
07 6.50 5.88 − 0.62
08 7.15 9.98 2.83
09 6.01 8.55 2.54
10 4.90 5.10 0.20
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