The Essentials of Biostatistics for Physicians, Nurses, and Clinicians

(Ann) #1
5.6 Exercises 71


  1. Ten diabetic patients had their plasma glucose levels (mmol/L) before and
    after 1 hour of oral administration of 100 g of glucose. The results are
    shown in Table 5.2.
    (a) Calculate the mean difference in plasma glucose levels.
    (b) Calculate the standard error of the mean.
    (c) Assuming a normal distribution for the change in plasma glucose.
    Based on the results in the table how many diabetic patients would
    you need to sample to get a 95% two - sided confi dence interval for
    the mean difference to have width 0.5 mmol/L? Treat the estimated
    standard error as if it were a known constant for this calculation.

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