Neuroanatomy Draw It To Know It

25. Sleep and Wakefulness 443

Ventrolateral peri-

aqueductal grey area

Dorsal paragiganto-

cellular reticular nucleus

Supraolivary

medulla

Sublaterodorsal

nucleus/peri-locus

coeruleus

Lateral hypothalamic

melanin-concentrating

hormone nuclei

Muscle

atonia

Cortex

REM EEG

dorsal deep mesen-

cephalic reticular nucleus

REM SLEEP CIRCUITRY

Voltage

Time

-65mV

T-type calcium

channels open

Low-threshold

spike

Refractory

period

Lateral

geniculate

Reticular

Nuclei

Thalamocortical

neurons

Cortical pyramidal

neurons

Thalamocortical neuronal

membrane potetnial

Sensory gating

NON-REM SLEEP CIRCUITRY

*Non-REM sleep induction

center lies within the

anterior hypothalamus

(ventrolateral preoptic area

& median preoptic nucleus)

DRAWING 25-1 Sleep Neurocircuitry