Mealey KL, Bentjen SA, Waiting DK (2002) Frequency of the mutant MDR1 allele associated
with ivermectin sensitivity in a sample population of collies from the northwestern United
States. Am J Vet Res 63:479–481
Mealey KL, Northrup NC, Bentjen SA (2003) Increased toxicity of P-glycoprotein-substrate
chemotherapeutic agents in a dog with the MDR1 deletion mutation associated with ivermectin
sensitivity. J Am Vet Med Assoc 223:1453–1455
Mealey KL, Greene S, Bagley R, Gay J, Tucker R, Gavin P, Schmidt K, Nelson F (2008) P-
glycoprotein contributes to the blood-brain, but not blood-CSF, barrier in a spontaneous canine
P-glycoprotein knockout model. Drug Metab Dispos 36:1073–1109
Medlicott NJ, Waldron NA, Foster TP (2004) Sustained release veterinary parenteral products.
Adv Drug Deliv Rev 56:1345–1365
Merino G, Alvarez AI, Pulido MM, Molina AJ, Schinkel AH, Prieto JG (2006) Breast cancer
resistance protein (BCRP/ABCG2) transports fluoroquinolone antibiotics and affects their oral
availability, pharmacokinetics, and milk secretion. Drug Metab Dispos 34:690–695
Miller JA, Davey RB, Oehler DD, Pound JM, George JE (2001) The Ivomec SR Bolus for control
ofBoophilus annulatus(Acari: Ixodidae) on cattle in South Texas. J Econ Entomol
94:1622–1627
Miller DS, Bauer B, Hartz AM (2008) Modulation of P-glycoprotein at the blood-brain barrier:
opportunities to improve central nervous system pharmacotherapy. Pharmacol Rev
60:196–209
Mills PC, Cross SE (2006) Transdermal drug delivery: basic principles for the veterinarian. Vet J
172:218–233
Mills PC, Cross SE (2007) Regional differences in transdermal penetration of fentanyl through
equine skin. Res Vet Sci 82:252–256
Mitri J, Pittas AG (2009) Inhaled insulin – what went wrong? Nat Clin Pract Endocrinol Metab
5:24–25
Murrell JC, Robertson SA, Taylor PM, McCown JL, Bloomfield M, Sear JW (2007) Use of a
transdermal matrix patch of buprenorphine in cats: preliminary pharmacokinetic and pharma-
codynamic data. Vet Rec 160:578–583
Nakagawa S, Deli MA, Kawaguchi H, Shimizudani T, Shimono T, Kittel A, Tanaka K, Niwa M
(2009) A new blood-brain barrier model using primary rat brain endothelial cells, pericytes and
astrocytes. Neurochem Int [Epub ahead of print] PMID: 19111869
Narahashi T, Zhao X, Ikeda T, Nagata K, Yeh JZ (2007) Differential actions of insecticides on
target sites: basis for selective toxicity. Hum Exp Toxicol 26:361–366
Naz RK, Gupta SK, Gupta JC, Vyas HK, Talwar AG (2005) Recent advances in contraceptive
vaccine development: a mini-review. Hum Reprod 20:3271–3283
Nicoletti P, Lenk RP, Popescu MC, Swenson CE (1989) Efficacy of various treatment regimens,
using liposomal streptomycin in cows with brucellosis. Am J Vet Res 50:1004–1007
Novotny MJ, Krautmann MJ, Ehrhart JC, Godin CS, Evans EI, McCall JW, Sun F, Rowan TG,
Jernigan AD (2000) Safety of selamectin in dogs. Vet Parasitol 91:377–391
Park HM, Han HR (2002) Production and characterization of biodegradable Povidone-iodine
microsphere as an intramammary disinfectant. J Vet Med Sci 64:739–741
Paul AJ, Tranquilli WJ, Seward RL, Todd KS, Di Pietro JA (1987) Clinical observations in Collies
given ivermectin orally. Am J Vet Res 48:684–685
Paul AJ, Tranquilli WJ, Hutchens DE (2000) Safety of moxidectin in avermectin-sensitive collies.
Am J Vet Res 61:482–483
Pekcec A, Unkru ̈er B, Stein V, Bankstahl JP, Soerensen J, Tipold A, Baumga ̈rtner W, Potschka H
(2008) Over-expression of P-glycoprotein in the canine brain following spontaneousstatus
epilepticus. Epilepsy Res [Epub ahead of print] PMID: 19059762
Ploegaert TC, De Vries Reilingh G, Nieuwland MG, Lammers A, Savelkoul HF, Parmentier HK
(2007) Intratracheally administered pathogen-associated molecular patterns affect antibody
responses of poultry. Poult Sci 86:1667–1676
Drug Delivery Systems in Domestic Animal Species 109