Heterocyclic Chemistry at a Glance, Second Edition. John A. Joule and Keith Mills.
© 2013 John Wiley & Sons, Ltd. Published 2013 by John Wiley & Sons, Ltd.
Items are listed alphabetically and ignoring prefi x numbers, hyphens, and Greek letters [however, e.g. ‘Pyridine, 2-lithio-’ will be found
before ‘Pyridine, 3-lithio-’]. In some cases the ‘correct’ order of substituents is not used, in order to emphasise the important func-
tional group, e.g. ‘3-lithio-1-tri-isopropylsilylindole’. To fi nd, e.g. 4-methylpyridine see ‘Pyridine, 4-methyl-’. Names containing, e.g.
‘dimethyl... ’ and ‘tribromo... ’ are listed under ‘d’ and ‘t’ respectively. Names such as ‘2-Pyridone’ are so listed and not as ‘pyridin-2-one’.
Index
A, see Adenine
Abilify 168
Acetamidine, in ring synthesis of an amino-pyrimidinone 59
Acetazolamide (Diamox) 175
Acetone peroxide 185
Acetyl nitrate 13
Acetylcholine (Ach) 169
Ach, see Acetylcholine
Acidity, defi nition 9
Actos 168
Acular 174
-Acylamino ketones, in ring synthesis of imidazoles 117
Acyclovir (Zovirax) 177
ortho-Acyl anilides in indole ring synthesis 96
Acyl radicals 14, 15
Acylhydrazides in ring synthesis of 1,3,4-oxadiazoles 139
Addition-elimination mechanism 13, 14
Adenine (A) 122, 123, 164
ring synthesis from formamide 131
Adenosine diphosphate (ADP) 123
Adenosine monophosphate (AMP) 123
Adenosine triphosphate (ATP) 123, 175
Adenosine 122, 123
ADP, see Adenosine diphosphate
Adrenaline 169, 173
Advanced glycation end products 189
formation 190
Afl atoxin B 1 192, 193
AGEs, see Advanced glycation end products
Agonists 168
AICA riboside, in ring synthesis of purines 131
AICA, see 5-Aminoimidazole-4-carboxamide
Air bag infl ators 185
ALA, see 5-Aminolevulinic acid
Alcohol dehydogenase 161
Alcoholic fermentation 161
Aldehydes from organolithium reagents 15, 16
from Vilsmeier reactions 12, 79, 88, 100
Alkaloids 165
3-Alkoxy-ene-ones, synthetic equivalents of 1,3-diketones 19
ortho-Alkylaryl isocyanides in indole ring synthesis 96
3-Alkylidene-indolenine 93
Alkynes, in ring synthesis of thiophenes 106
Alkynyl-ketones in ring synthesis of pyrazoles 120
Alprazolam (Xanax) 173
Ambien 173
Amidines, in ring synthesis of imidazoles 118
Amidrazone 136
Aminoacetal, see Aminoacetaldehyde dimethyl acetal
Aminoacetaldehyde dimethyl acetal, in ring synthesis
of isoquinolines 69
-Amino acid 158
decarboxylation, enzyme catalysed 161
ortho-Aminoarylalkynes, in ring synthesis of indoles 96
-Aminobutyric acid 169
-Amino esters, dimerisation 60
5-Aminoimidazole-4-carboxamide (AICA) 131
-Amino ketones
dimerisation to dihydropyrazines 84
from acid chlorides 60
from -amino acids 84
from -keto-oximes 84
in ring synthesis of pyrazines 60
of pyrroles 83, 84
-Aminolevulinic acid, see 5-Aminolevulinic acid
5-Aminolevulinic acid (ALA) 163, 179
Amlodipine (Norvasc)
AMP, see Adenosine monophosphate
Amylobarbitone 173
Angelica lactone 104
Anilines, in ring synthesis of quinolines 68
Anomeric effect 154
ANRORC processes 50, 57, 65, 124, 129
Antagonists 168
histamine (H 2 ) 170
Anthocyanins 165
Anthranilic acid, in ring synthesis of a 4-quinazolinone 61
N-ethyl-, in isatin synthesis 97
Anthrax 176
Antihistamines 170
Antihypertensive agent 45
Antilinum 172
Antipyrine, see 2,3-Dimethyl-1-phenylpyrazol-5-one
Apresoline 173
L-Arginine 189
Aripiprazole (Abilify) 168
Aristeromycin 123
Aromaticity 4