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1
How to Use Herbs, Nutrients & Yoga in Mental Health Care, by Richard P. Brown, M.D. (of Columbia University
College of Physicians and Surgeons), Patricia L. Gerbarg, M.D. (of New York Medical College), and Philip R. Muskin,
M.D. (of Columbia as well) (W. W. Norton & Company, New York 2009), at 160-161.
(^2) Id.
(^3) Rodale Press, Emmaus, PA (2004).
(^4) Bytstritsky, A., Kerwin, L. & Feusner, J.D., “A Pilot Study of Rhodiola rosea (Rhodax) For Generalized Anxiety
Disorder,” Journal of Alternative and Complementary Medicine 14(2):175-180 (2008).
(^5) Muskin, P.R., Gerbarg, P.L., and Brown, R.P., Complementary and Integrative Therapies for Psychiatric Disorders,
Psychiatric Clinics of North America, copyright Elsevier, Inc., Philadelphia ( 2013 ) (“Brown et al. II”) at 54.
(^6) Darbinyan, V., Kteyan, A., Panossian, A., Gabrielian, E., Wikman, G. & Wagner, H., “Rhodiola rosea in Stress-
induced Fatigue – A Double-blind Cross-over Study of a standardized Extract SHR-5 with a Repeated Low-dose
Regimen on the Mental Performance of Healthy Physicians During Night Duty,” Phytomedicine 7:365-371 (2000).
(^7) Spasov, A.A., Wikman, G.K., Mandrikov, V.B., Mironova, L.A. & Neumoin, W., “A Double-blind Placebo-controlled
Study of the Stimulating and Adaptogenic Effect of Rhodiola rosea SHR-5 Extract on the fatigue of Students Caused
by Stress during an Examination Period with a Repeated Low-dose Regimen,” Phytomedicine 7:85-89 (2000).
(^8) In addition to rhodiola, the proprietary formula includes roseroot, vitamin E, vitamins B6 and B12, folate and
magnesium.
(^9) Fintelmann, V. & Gruenwald, J., “Efficacy and Tolerability of a Rhodiola Rosea Extract in Adults With Physical and
Cognitive Deficiencies,” Advances in Therapy 24(4):929-939 (2007).
(^10) Darbinyan, V, Aslanyan, G, Amroyan, E, Gabrielyan E, Malmström, C & Panossian, A., “Clinical Trial of Rhodiola
Rosea L. Extract SHR-5 in the Treatment of Mild to Moderate Depression,” Nord. J. Psychiatry. 61(5):343- 8 (2007).
All further references to Darbinyan et al. are to this study.
(^11) Weil, A., Spontaneous Happiness (Little, Brown and Company, New York 2011), at 116.
(^12) Id.
(^13) Brichenko,V.S., Kupriyanova, I.E., Skorokhadova, T.F., “The Use of Herbal Adaptogens Together with Tricyclic
Anti-depressants in Patients with Psychogenic Depressions,” in Goldberg, E.D. (Ed.) Modern Problems of
Pharmacology and Search for New Medicines, vol. 2 (Tomsk State University Press, Tomsk, Russian Republic,
former Soviet Union, 1986); Brichenko, V.S.and Skorokhodova,T.F., “Herbal Adaptogens in Rehabilitation of
Patients with Depressions,” in: Clinical and Organizational Aspects of Early Manifestations of Nervous and Mental
Diseases (Barnaul 1987).
(^14) Brown et al. II at 54.
(^15) Gerbarg, P.L., Brown, R.P., “Phytomedicines for Prevention and Treatment of Mental Health Disorders,”
Psychiatric Clinics of North America 3 5(1):_____( 2013 ); Panossian, A., Hovhannisyan, A., Abrahamyan, H., et al.
“Pharmacokinetic and Pharmacodynamic Study of Interaction of Rhodiola Rosea SHR- 5 Extract with Warfarin and
Theophylline in Rats,” Phytother Res 23(3):351– 7 (2009).