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Other common side effects, such as nausea, loose stools, and sun sensitivity, are easily
addressed by taking food with each dose and using sunscreen.
There are insufficient data available at this time to recommend use of St. John’s wort by
children or during pregnancy or breast-feeding.Drug Interactions
St. John’s wort has serious potential interactions with many prescription medications, including
antidepressants, birth control medications and others. The use of St. John’s wort should
always be discussed with the prescribing physician.
CONCLUSION
St. John’s wort is a commonly-taken and well-supported treatment for mild to moderate
depression. It may have other benefits, but also has serious risks of drug interactions.
Adjunctive use with antidepressants requires caution and strict coordination with the
prescribing physician. Long-term use also requires consultation with a health care practitioner.