7. SIDE EFFECTS
Valerian can cause mild side effects, such as occasional gastrointestinal effects,
headaches, dizziness, excitability, uneasiness, unsteadiness, low body temperature,
tiredness the morning after its use,^9 and a “hangover” from large doses. Similarly,
"valerian withdrawal" may occur if the consumer stops using the drug suddenly after
long-term high-dose use. This may entail confusion and rapid heartbeat. These
symptoms may improve with the use of benzodiazepines such as lorazepam (Ativan).
Valerian is classified by the FDA as: "generally regarded as safe," and Fugh-Berman and
Cott refer to valerian as “quite safe.” Slight reductions in concentration and complicated
thinking may occur for few hours after taking the drug. Use caution if driving or
operating heavy machinery, since valerian can cause “impaired vigilance” for a few
hours after ingestion, according to Lake and Spiegel. Long-term use may result in
insomnia.
Toxic reactions from valerian are rare but may include blurred vision and dystonia
(a neurological movement disorder in which sustained muscle contractions cause
twisting and repetitive movements or abnormal postures).
Valerian has an unpleasant taste and odor. One advantage of valerian over other
sedatives and hypnotics is that there have been no reported cases of valerian
habituation or abuse and only one case of possible withdrawal symptoms.
- CONCLUSION: Since it appears relatively safe so long as drug interactions are avoided,
valerian may be a CAM support to help with sleep even if it can’t cure chronic insomnia.
- DOSAGE: The Natural Standard states that doses range from 400 to 900 mg per day of
aqueous or aqueous-ethanol extract, corresponding to 1.5 to 3 g of the drug, taken 30 to 60
minutes before going to bed. But the “recommended dose” listed by Mischoulon and
