PTSD
Case reports showed promising possibilities for the effects of 7-keto DHEA on PTSD; however,
there are still inadequate clinical studies supporting this use.
Schizophrenia
Two trials of DHEA treatment in people with schizophrenia showed a reduction in negative
symptoms, and experts theorize that there may be a deeper connection. But there isn’t enough
research to show that DHEA is particularly promising or effective for this use.
Cognition
Recent trials do not support the use of DHEA for neuroprotection.
7 - KETO DHEA
7 - keto-DHEA is a byproduct of DHEA. But unlike DHEA, 7-keto-DHEA is not converted to steroid
hormones such as androgen and estrogen. Taking 7-keto-DHEA by mouth or applying it to
the skin does not increase the level of steroid hormones in the blood. Thus, 7-keto DHEA
deserves study to determine whether it has the same efficacy as DHEA without the hormonal
side effects.
DRUG INTERACTIONS AND SIDE EFFECTS
Drug Interactions: If you are considering taking or continuing to take DHEA or 7-keto DHEA, you
should definitely consult with a skilled health care practitioner. It is critical to consult with your
prescribing physician if you are taking any psychotropic medication.
DHEA may interfere with a wide variety of prescription medications, over-the-counter
medications, and other herbal supplements. DHEA may also interact with a recent flu
vaccination or with alcohol consumption. As a result, great care should be taken before
supplementing DHEA levels. No prescription medication should be taken with DHEA without
consulting with the prescribing physician. The following list is illustrative only.