HERBAL MONOGRAPHS UVA-URSI/781macerations, and also as extracts and solid forms for oral
administration. It is also a component of urologic combina-
tion and single-component preparations.How Supplied:Capsules—150 mg, 455 mg, 505 mg
TeasSolutions
Preparation: To make a tea, pour boiling water over 2.5 gm
finely cut or coarse powdered drug (l teaspoonful is
equivalent to 2.5 g drug.), or place the drug in cold water that
is rapidly brought to a boil. The tea should draw (to extract
the essence) for 15 minutes and then be strained. Teas may
contain up to 30% Uva-Ursi in combination with other
drugs. For higher Uva-Ursi content, prepare cold macerate
(over 6 to 12 hours) to lower the tannin content.
Daily Dosage: The daily dosage of finely cut or powdered
drug is 10 g (corresponding to arbutin content of 400 to 840
mg) or 0.4 g dry extract in a single dose. A single dose of
liquid extract is 2 g. Daily dosages of an infusion or cold
maceration are 3 g drug to 150 ml water as an infusion or
cold maceration up to 4 times a day or 400 to 840 mg
hydroquinone derivatives calculated as water-free arbutin.
The urine should be alkaline.
Homeopathic Dosage: 5 to 10 drops, 1 tablet or 5 to 10
globules 1 to 3 times daily or 1 ml injection solution twice
weekly sc (HAB1).
Storage: Store in well-sealed containers protected from light.
LITERATURE
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nigra L. and Arctostaphylos uva-ursi (L.) Spreng, in rats.
Phytother Res 1999 May;13(3):222-5.
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Matsuda H et al., Pharmacological studies on leaf of
Arctostaphylos uva-ursi: Effect of 50% methanolic extract from
Arctostaphylos uva-ursi on melanin synthesis. Yakugaku Zasshi,
112:276-82, 1992 Apr
Matsuda H et al., Pharmacological studies on leaf of
Arctostaphylos uva-ursi: Effect of water extract from
Arctostaphylos uva-ursi on the antiallergic and anti-
inflammatory activities of dexamethasone ointment. Yakugaku
Zasshi, 112:673-7, 1992 Sep.
Matsuda H, Nakata H, Tanaka T, Kubo M, Phenolic acids in
leaves of Arctostaphylos uva ursi L. Vaccinium vitis idaea L.
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study on Arctostaphylos uva-ursi (L.) Spreng. II. Combined
effects of arbutin and prednisolone or dexamethazone on
immuno-inflammation. Yakugaku Zasshi, 110:68-76, 1990 Jan.
Matsuo K, Kobayashi M, Takuno Y, Kuwajima H, Ito H,
Yoshida T, Anti-tyrosinase activity constituents of
Arctostaphylos uva-ursi. Yakugaku Zasshi, 117:1028-32, 1997
Dec.
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Further information in:
Hansel R, Keller K, Rimpler H, Schneider G (Hrsg.), Hagers
Handbuch der Pharmazeutischen Praxis, 5. Aufl., Bde 4-6
(Drogen): Springer Verlag Berlin, Heidelberg, New York, 1992-
1994.