PDR for Herbal Medicines

804 /WHITE HELLEBORE

the alkaloid mixture, corresponding to 1 to 2 gm of the drug.

The alkaloids can be absorbed through uninjured skin.

Treatment of poisoning consists of gastrointestinal emptying

(inducement of vomiting, gastric lavage with burgundy-

colored potassium permanganate solution, sodium sulphate),

administration of activated charcoal and shock prophylaxis

(appropriate body position, quiet, warmth). Thereafter,

spasms should be treated with diazepam or barbiturates (i.v.),

bradycardia should be treated with atropine, hypotension

should be treated with peripherally active circulatory medi-

cations, electrolyte substitution should be employed, and

possible cases of acidosis should be treated with sodium

bicarbonate infusions. Intubation and oxygen respiration may

also be necessary.

DOSAGE

Mode of Administration: The drug is used in powders,

tinctures and homeopathic dilutions for internal use; prepara-

tions made with fatty oils are used externally.

Preparation: Mix 5 gm drug with 10 gm lanolin and 20 gm

fat for topical application.

Daily Dosage: Internally, the drug is administered as 0.02 to

0.1 gm of powder or 20 to 60 drops of tincture. Externally,

the drug is applied as a poultice or compress.

Homeopathic Dosage: 5 drops, 1 tablet or 10 globules every

30 to 60 minutes (acute) and 1 to 3 times daily (chronic);

parenterally: 1 to 2 ml s.c, acute: 3 times daily; chronic:

once a day (HAB34). The globules are from D2; all others

are from D4.

LITERATURE

Atta-Ur-Rahman, Ali RA, Choudhary MI, New steroidal

alkaloids from rhizomes of Veratrum album. In: JNP 55:565-

570. 
     
     
     
     1992. Atta-Ur-Rahmann, Ali RA, Gilani A, Choudhary MI, ASftab K,
           Sener B, Turkz S, Isolation of antihypertensive alkaloids from
           rhizomes of Veratrum album. In: PM 59(6):569. 1993.
           Atta-Ur-Rahman et al., Alkaloids from Veratrum album. In: PH
           30(1):368. 1991.
           Brossi, Buch. In: Brossi A, Cordell GA (Eds), The Alkaloids.
           Vol. 41. Academic Press, 1250 Sixth Avenue, San Diego, CA.
     
     
     
     


571. 
     
     
     
     1992. Festa M, Andreetto B, Ballads MA, Panio A, Piervittori R, A
           case of Veratrum poisoning. Minerva Anestesiol, 62:195-6, 1996
           May.
           Fogh A, Kulling P, Wickstrom E, Veratrum alkaloids in
           sneezing-powder a potential danger. J Toxicol Clin Toxicol,
           20:175-9, 1983 Apr.
     
     
     
     

Gamier R, Carlier P, Hoffelt J, Savidan A, Acute dietary
poisoning by white hellebore (Veratrum album L.). Clinical and
analytical data. A propos of 5 cases. Ann Med Interne (Paris),
136:125-8, 1985.

PDR FOR HERBAL MEDICINES

Hruby K, Lenz K, Krausler J, Veratrum album poisoning

(author's transl). Wien Klin Wochenschr, 93:517-9, 1981 Sep 4.

Jaspersen-Schib R, Theus L, Guirguis-Oeschger M, Gossweiler

B, Meier-Abt PJ, Serious plant poisonings in Switzerland 1966-

1994. Case analysis from the Swiss Toxicology Information
      Center. Schweiz Med Wochenschr, 60:1085-98, 1996 Jun 22.
      Marinov A, Koev P, Mirchev N, Electrocardiographic studies of
      patients with acute hellebore (Veratrum album) poisoning. Vutr
      Boles, 26:36-9. 1987.
      Further information in:
      Frohne D, Pfander HJ, Giftpflanzen - Ein Handbuch fur
      Apotheker, Toxikologen und Biologen, 4. AufL, Wiss. Verlags-
      Ges. Stuttgart 1997.
      Kern W, List PH, Horhammer L (Hrsg.), Hagers Handbuch der
      Pharmazeutischen Praxis, 4. AufL, Bde. 1-8: Springer Verlag
      Berlin, Heidelberg, New York, 1969.
      Lewin L, Gifte und Vergiftungen, 6. Aufl., Nachdruck, Haug
      Verlag, Heidelberg 1992.
      Madaus G, Lehrbuch der Biologischen Arzneimittel, Bde 1-3,
      Nachdruck, Georg Olms Verlag Hildesheim 1979.
      Roth L, Daunderer M, Kormann K, Giftpflanzen, Pflanzengifte,


1995. Aufl., Ecomed Fachverlag Landsberg Lech 1993.
      Teuscher E, Lindequist U, Biogene Gifte - Biologie, Chemie,
      Pharmakologie. 2. Aufl., Fischer Verlag Stuttgart 1994.
      Teuscher E, Biogene Arzneimittel, 5. Aufl., Wiss. Verlagsges.
      Stuttgart 1997.
      Wagner H, Wiesenauer M, Phytotherapie. Phytopharmaka und
      pflanzliche Homdopathika, Fischer-Verlag, Stuttgart, Jena, New
      York 1995.

White Lily

Lilium candidum

DESCRIPTION

Medicinal Parts: The medicinal part is the fresh and dried

bulb.

Flower and Fruit: The inflorescence has 5 to 20 blossoms.

The flowers are white, occasionally striped crimson or

spotted and very fragrant. They are on erect pedicles, the

lower ones nodding. The tepals are obtuse, the anthers

yellow. The style is as long as the sepals. The fruit is obovate

and is seldom developed.

Leaves, Stem and Root: The plant is perennial, 60 to 150 cm

high. It has a broad, ovate, scaled and yellow bulb. The stem

is rigid, erect and leafy. The leaves are oblong to linear-

lanceolate and glabrous. The leaves survive winter, as does

the rest of the plant, which is hardy. The bulb consists of

imbricate, fleshy, lanceolate and bent scales, which are 3.25

cm long and 2.5 cm wide at the broadest point.