1-182/DIGITALIS PDR FOR HERBAL MEDICINESQuinidine
(Increases risk of cardiac
arrhythmias)
Sympathomimetic Agents
(Increases risk of cardiac
arrhythmias)
DIGITALIS GLYCOSIDE PREPARATIONS
Licorice
(Licorice-induced hypokalemia
increases risk of digitalis toxicity)
Rauwolfia
(Severe bradycardia when used in
combination with digitalis
glycosides)
Senna
(Senna-induced hypokalemia may
increase toxicity of digitalis
preparations)
DIGITALIS LANATA
Methylxanthines
(Risk of cardiac arrhythmias)
Phosphodiesterase Inhibitors
(Risk of cardiac arrhythmias)
Quinidine
(Risk of'cardiac arrhythmias)
Sympathomimetic Agents
(Risk of cardiac arrhythmias)
DIGITALIS PURPUREA
(See under Digitalis)
DIGOXIN
Adonis
(Increases action of Adonis)
Buckthorn
(Herb may cause hypokalemia,
which may increase digoxin
toxicity)
Cascara Sagrada
(Herb may cause hypokalemia,
which may increase digoxin.
toxicity)
Chinese Rhubarb
(Herb may cause hypokalemia,
which may increase digoxin
toxicity)
Frangula
(Herb may cause hypokalemia,
which may increase digoxin
toxicity)
Guarana
(Herb may cause hypokalemia,
which may increase digoxin
toxicity)
Lily-of-the-Valley
(Increases the effect of Lily-of-
the-Valley)
Squill
(Squill potentiates the positive
inotropic and negative chronopic
effects of digoxin)
St. John's Wort
(Co-administration of the herb
with digoxin has resulted in a
significant decrease in the digoxin
area under the curve)
Uzara
(Herb contains cardiac glycosides
and may have additive effect
when taken with digoxin, possibly
increasing digoxin toxicity)
DIOSCOREA VILLOSA
(See under Wild Yam)
DIURETICS
Kombe Seed
(Increases effects and side effects
of herb)
DOPAMINE ANTAGONISTS
Chaste Tree
(Decreased dopaminergic effect of
herb)
DRUGS THAT CAUSE
THROMBOCYTOPENIA
Quinine
(Herb increases risk of
thrombocytopenia)
DRUGS, UNSPECIFIED
Coffee
(Herb can hinder (or decrease)
resorption of other drugs)
Flax
(Absorption of other drugs may
be delayed when taken
simultaneously)
Niauli
(Co-administration may result in
decreased effect of drugs that
undergo liver metabolism)
Psyllium
(Absorption of other drugs may
be decreased if taken
simultaneously with herb)
Psyllium Seed
(Absorption of other drugs may
be decreased if taken
simultaneously with herb)ECHINACEA ANGUSTIFOLIA
Corticosteroids
(Echinacea may potentially
interfere with the anti-cancer
chemotherapeutic effect of
corticosteroids)
Immunosuppressants
(The immune-stimulating effect of
Echinacea may interfere with
drugs that have
immunosuppressant effects)
EPHEDRA SINICA
(See under Ma-Huang)
ESTROGEN
Senna
(Senna decreases estrogen levels
when taken with estrogen
supplements)
Wild Yam
(Additive effect)
ETHANOL
Yohimbe Bark
(Increased anxiogenic effects)
EVENING PRIMROSE
Anticonvulsants
(Evening Primrose oil may lower
seizure threshold and decrease
effectiveness of anticonvulsant
medications)
FENUGREEK
Hypoglycemic Drugs
(Herb may have an additive
hypoglycemic effect when taken
with other hypoglycemic drugs)
FEVERFEW
Aspirin
(Increased antithrombotic effect)
Warfarin Sodium
(Increased antithrombotic effect)
FLAX
Drugs, unspecified
(Absorption of other drugs may
be delayed when taken
simultaneously)
FRANGULA
Cardiac Glycosides
(Increased effect due to potassium
loss with chronic use of herb)