PDR for Herbal Medicines

(Barré) #1
152/CAROB PDR FOR HERBAL MEDICINES

stemmed ovaries. The pods are 10 to 20 cm by 2 cm, tough
leathery, brown-violet, flat and often rounded to a horn
shape. There are numerous, lumpy and glossy brown seeds.

Leaves, Stem and Root: This walnut-like tree is usually
under 6 m high, broad-crowned, sparsely branched and with
cracked gray-brown bark. There are 2 to 4 paired pinnate
leaves. The leaflets are obovate, 4 to 5 cm long, curved,
glabrous, glossy dark green above and red-brown beneath.

Habitat: Indigenous to southeastern Europe and west Asia,
otherwise cultivated.

Production: Carob seed flour is the ground endosperm of the
seeds of Ceratonia siliqua.

Not to be Confused With: Carob Tree, Jacaranda procera or
Jacaranda caroba.

Other Names: St. John's Bread, Locust Bean, Locust Pods,
Sugar Pods

ACTIONS AND PHARMACOLOGY
COMPOUNDS
Mucilages: chiefly made up of galactomannanes

Proteic substances

Flavonoids: including isoschaftoside, neoschaftoside,
schaftoside

EFFECTS
In various test series and studies, the effect of carob gum on
the serum glucose level, the secretion and activity of
digestive enzymes, the secretion of gastrointestinal hormones
as well as on the serum lipid level was proven. The
hypoglycaemic and hypolipidaemic effect is attributed to an
increase in viscosity of the gastrointestinal content.

Effects on nitrogen balance, efficacy in infantile diarrhea, as
well as an anti-exudative, anticoagulant and antiviral effects
have been demonstrated.

INDICATIONS AND USAGE
Unproven Uses: Carob is used in dietary agents for acute
nutritional disorders, diarrheal disorders, dyspepsia, entero-
colitis, celiac disease and sprue. It is also used for habitual
vomiting in babies, acetonemic vomiting, rumination, retch-
ing cough and vomiting.

Carob seed flour is used in the production of glutin-free
starch bread, which is used for vomiting during pregnancy,
celiac disease and obesity.

PRECAUTIONS AND ADVERSE REACTIONS
No health hazards or side effects are known in conjunction
with the proper administration of designated therapeutic
dosages.


DOSAGE
Mode of Administration: It is obsolete as a drug but is
included in thickening powders and as a baking aid for
glutin-free starch bread.

Preparation: As a baking aid or thickening agent, dissolve in
cold liquid, boil for 1 to 2 minutes, cool and mix into the
prepared baby food.
Daily Dosage: For a 3 to 10% arabon preparation, add 20 to
30 mg of drug to water, tea or milk, to be drunk during the
course of the day. As a baking agent in glutin-free bread for
babies, add 1/4 to 1/2 gm of drug (max. 2 gm) to 100 ml
liquid; adults 1% to 3% additive to low-calorie starters and
desserts.
LITERATURE
Kern W, List PH, Horhammer L (Hrsg.), Hagers Handbuch der
Pharmazeutischen Praxis, 4. Aufl., Bde 1-8, Springer Verlag
Berlin, Heidelberg, New York, 1969.
Leung AY, Encyclopedia of Common Natural Ingredients Used
in Food Drugs and Cosmetics, John Wiley & Sons Inc., New
York 1980.
McLeary BV, Biomass A Cellulose and Hemicellulose 160:523.
1988.
Steinegger E, Hansel R, Pharmakognosie, 5. Aufl., Springer
Verlag Heidelberg 1992.
Tang W, Eisenbrand G, Chinese Drugs of Plant Origin,
Springer Verlag Heidelberg 1992.
Teuscher E. Biogene Arzneimittel, 5. Aufl., Wiss. Verlagsges.
mbH Stuttgart 1997.

Carrageen


Chondrus crispus
DESCRIPTION
Medicinal Parts: The medicinal part of carrageen, the Irish
seaweed, is the thallus that has been freed from the adhesive
disc then dried and bleached in the sun.
Flower and Fruit: Gamatangia: The spematangia are color-
less and are at the end of the younger thaljus lobes. The
spermatia are 7.5 to 10 p:m long and 4 to 5 p:m wide; the
carposporangia are 20 to 20 jim long and 14 to 25 \\m wide
and have no outer threads. The tetrasporangia, along with the
cruciform arranged tatra spores, are in the'medulla of the
short side branches.

Thallus: Chondrus crispus is a perennial red algae that grows
in waters up to 25 m deep. The thallus is usually yellow-
green to purplish-brown when fresh, white to yellow and
translucent after drying. Thallus fronds, are 10 to 30 cm long
on an adhesive disc, arising from a subcylindrical stem. They
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