162 /CAT'S CLAW PDR FOR HERBAL MEDICINESuntil there is about 500 ml liquid remaining. Allow to cool,
then strain and refrigerate (Schauss, 1998).
How Supplied:
Capsule — 250 mg, 350 mg, 400 mg, 440 mg, 500 mg, 505
mg, 540 mgLiquid — 4:1
Daily Dosage: The daily dosage is 250 to 1000 mg daily.
The total alkaloid equivalent should be 10 to 30 mg.
Decoction dosage is 60 ml once daily in the morning on an
empty stomach (Schauss, 1998).
Storage: Cat's Claw should be stored at room temperature
away from heat, moisture and direct light.
LITERATURE
Aquino R, De Feo V, De Simone F et al: Plant metabolites:
new compounds and anti-inflammatory activity of Uncaria
tomentosa. J Nat Prod 54(2):453-459. 1991.
Chen C, et al., Inhibitory effect of rhynchophylline on platelet
aggregation and thrombosis. In: Chung Kuo Yao Li Hsueh Pao,
13(2); 126-30, Mar. 1992.
Cabieses, Fernando. The saga of the Cat's Claw, In: Via
Lactera Editores: Lima, Peru, 1994.
Hilepo JN, Bellucci AG & Mossey RT: Acute renal failure
caused by "cat's claw" herbal remedy in a patient with
systemic lupus erythematosus (letter). Nephron 77(3):36I-369.
1997.
Horie S, et al.. Effects of hirsutine, an antihypertensive indole
alkaloid from Uncaria rhynchophylla, on intracellular calcium in
rat thoracic aorta. In: Life Sci, 50(7):491-8, 1992.
Lemaire I, Assinewe V, Cano P et al: Stimulation of
interleukin-1 and -6 production in alveolar macrophages by the
neotropical liana, Uncaria tomentosa (una de gato). J
Ethnopharmacol 64(2): 109-115. 1999.
Nakazawa K, et al.. Inhibition of ion channels by hirsutine in
rat pheochromocytoma cells. In: Jpn J Pharmacol, 57(4):507-15,
Dec, 1991.
Obregon LE: Identificacion correcta de "una de gato" (genero
Uncaria). Natura Medicatrix 40(summer):28-30. 1995.
Rodriguez H, Massey PJ, Rodriguez K et al: Inhibition of
steroid hormone production by a nutrition supplement "una de
gato" or "cat's claw." Biol Reprod 58(1):208. 1998.
Salazar EL & Jayme V: Depletion of specific binding sites for
estrogen receptor by Uncaria tomentosa. Proc Western
Pharmacol Soc 41:123-124. 1998.
Schauss AG: Cat's Claw (Uncaria tomentosa). Nat Med J 1998;
1(2): 16-19.
Senatore A, Cataldo A, Iaccarino FP et al: Ricerche
fitochimiche e biologiche sull? Uncaria tomentosa (Italian). Boll
Soc Ital Biol Sper 65:517-520. 1989.Sheng Y, Pero RW, Amiri A et al: Induction of apoptosis and
inhibition of proliferation in human tumor cells treated with
extracts of Uncaria tomentosa. Anticancer Res 18(5A):3363-
- Shi J, et al., Effects of rhynchophylline on motor activity of
mice and serotonin and dopamine in rat brain. In: Chung Kuo
Yao Li Hsueh Pao, 14(2): 114-117, Mar, 1993.
- Shi J, et al., Effects of rhynchophylline on motor activity of
Cat's Foot
Antennaria dioicaDESCRIPTION
Medicinal Parts: The medicinal part is the flower.Flower and Fruit: The plant has bright red and white,
dioecious composite flowers. They are very small and are in
terminal cymes. The female flowers are bright red with
thread-like, cylindrical corolla. The male flowers are white
with a funnel-shaped corolla. The bracts of the male are
white, the female, pink. The fruit has a tuft of hair.Leaves, Stem and Root: The plant is 7 to 20 cm tall, with
leafy rooting runners. The stem is erect with basal leaves that
are spatulate, green above, gray beneath, cauline, linear and
erect.Habitat: Cat's Foot is found in Europe, Asia and America as
far north as the Arctic.Production: Cat's Foot flower consists of the fresh or dried
flowers of Antennaria dioica.Not to be Confused With: Occasional confusion occurs with
die flower heads of Helichrysum stoechas or Helichrysum
angustifolium.Other Names: Mountain Everlasting, Life Everlasting,
CudweedACTIONS AND PHARMACOLOGY
COMPOUNDS
Anthracene derivativesFlavonoids: including luteolin and its glucosidesBitter substancesMucilagesSaponinsTanninsEFFECTS
In animal tests, a mild spasmolytic and choleric effect has
been reported.