HERBAL MONOGRAPHS CELANDINE/171Infusion — 15 gm dried herb to 1 liter of water, leave to
draw for 15 minutes.Daily Dosage: The average daily dose is 2 to 4 gm of drug in
liquid or solid extracts, equivalent to 12 to 30 mg total
alkaloids calculated as chelidonine; fluid extract, 1 to 2 ml
three times daily; decoction, 3 cups daily; infusion, 3 cups
between meals.Storage: Celandine herb should be protected carefully from
light.CELANDINE ROOT
Mode of Administration: Most standardized and compound
preparations contain the extract of Celandine herb; various
homeopathic preparations also contain dilutions of the fresh
herb Greater Celandine.Daily Dosage: The standard dose is 0.5 gm of drug.Homeopathic Dosage: 5 drops, 1 tablet, 10 globules every 30
to 60 minutes (acute) or 1 to 3 times daily (chronic);
parenterally: 1 to 2 ml sc acute: 3 times daily; chronic: once
daily (HAB1).Storage: Preparations must be stored carefully.
LITERATURE
CELANDINE HERB
Aberlein H et al., Chelidonium majus L, Components with in
vitro affinity for GABA A receptor. Positive cooperation of
alkaloids. In: PM 62(3):227-231. 1996.
Anonym, Brennpunkt ZNS. In: DAZ 137(25):2166-2167. 1997.
Amason JT, Gurein B, Kraml MM, Mehta B. Rehmond JC,
Scaiano JC, Phototoxic and photochemical properties of
sanguinarin. In: Photochemistry and Photobiology 55(1 ):35.
1992.
Baumann J, (1975) Ober die Wirkung von Chelidonium,
Curcuma, Absinth und Carduus marianus auf die Galle- und
Pankreassekretion bei Hepatopathien. Med Mschr 29:173.
Boegge SC et al., Reduction of ACh-induced contraction of rat
isolated ileum by Coptisin, Caffeoylmalic acid, Chelidonium
majus, and Corydalis lutea extracts. In: PM 62(2): 173-174.
1997.
Diener H, Schollkraut. In: PTA 8(2): 145. 1994.
Dostal J et al.. Structure of chelerythrine base. In: JNP
58(5):723-729. 1995.Fulde G, Wichtl M, Analytik von Schollkraut, Hauptalkaloid
Coptisin. In: DAZ 134(12): 1031. 1994.
Hahn R, Nahrstedt A, Hydroxycinnamic acid derivatives,
caffeoylmalic and new caffeoylaldonic acid esters, from
Chelidonium majus. In: PM 59(1):71. 1993.
Hamacher H, Haben Phytopharmaka eine Zukunft? In: DAZ
131(42):2155. 1991.
Kim DJ, Ahn B, Han BS, Tsuda H, Potential preventive effects
of Chelidonium majus L (Papaveraceae) herb extract on
glandular stomach tumor development in rats treated with N-
methyl-N'-nitro-N nitrosoguanidine (MNNG) and hypertonic
sodium chloride. In: Can..
Mitra S et al., Effect of Chelidonium majus L. on experimetal
hepatic tissue injury. In: Phytother Res 10(4):354-356. 1996.
Reuter HD, Pflanzliche Gallentherapeutika (Teil I) und (Teil II).
In: ZPT 16(1): 13-20 u. 77-89. 1995.
Schilcher H, Pharmazeutische Aspekte pflanzlicher
Gallentherapeutika. In: ZPT 16(4):211-222. 1995.
Schmidt M, Phytotherapie: Pflanzliche Gallenwegstherapeutika.
In: DAZ 135(8):680-682. 1995.
Taborska E et al.. The alkaloids of Chelidonium majus L. and
their variability. In: PM 62, Abstracts of the 44th Ann
Congress of GA, 145. 1996.
Vahlensiek U et al., The effect of Chelidonium majus herb
extract on the choleresis in the isolated perfused rat liver. In:
PH 61(3):267-270. 1995.
Vavreckova C, Gawlik I, Miiller K, Benzophenanthridine
alkaloids of Chelidonium majus: I. Inhibition of 5- and 12-
lipoxygenase by a non-redox mechanism. In: PM 62(5):397-401.
1996.
Willaman JJ and Hui-Li L, (1970) Lloydia 33 (3A):1.
Further information in:
Chan, EH et al., (Eds), Advances in Chinese Medicinal
Materials Research, World Scientific Pub. Co. Singapore 1985.
Frohne D, Pfander HJ, Giftpflanzen - Ein Handbuch fur
Apotheker, Toxikologen und Biologen, 4. Aufl., Wiss.
Verlagsges. mbH Stuttgart 1997.
Hansel R, Keller K, Rimpler H, Schneider G (Hrsg.), Hagers
Handbuch der Pharmazeutischen Praxis, 5. Aufl., Bde 4-6
(Drogen): Springer Verlag Berlin, Heidelberg, New York, 1992-
1994.
Lewin L, Gifte und Vergiftungen, 6. Aufl., Nachdruck, Haug
Verlag, Heidelberg 1992.
Madaus G, Lehrbuch der Biologischen Arzneimittel, Bde 1-3,
Nachdruck, Georg Olms Verlag Hildesheim 1979.
Roth L, Daunderer M, Kormann K, Giftpflanzen, Pflanzengifte,- Aufl., Ecomed Fachverlag Landsberg Lech 1993.
Schulz R, Hansel R, Rationale Phytotherapie, Springer Verlag
Heidelberg 1996.
Steinegger E, Hansel R, Pharmakognosie, 5. Aufl., Springer
Verlag Heidelberg 1992.
Teuscher E, Lindequist U, Biogene Gifte - Biologie, Chemie,
Pharmakologie, 2. Aufl., Fischer Verlag Stuttgart 1994.
Teuscher E, Biogene Arzneimittel, 5. Aufl., Wiss. Verlagsges.
mbH Stuttgart 1997.
Wagner H, Wiesenauer M, Phytotherapie. Phytopharmaka und
pflanzliche Homoopathika, Fischer-Verlag, Stuttgart, Jena, New
York 1995.