PDR for Herbal Medicines

HERBAL MONOGRAPHS CETRARIA ISLANDICA/175

INDICATIONS AND USAGE

Approved by Commission E:

• Dyspeptic complaints


• Loss of appetite •
  ** Unproven Uses: The drug is used for loss of appetite,
  dyspepsia and poor gastric secretion. In folk medicine, it is
  used for fever, worm infestation and as a hypotensive. It is
  also used for diabetes in Mallorca, and for expelling kidney
  stones in Egypt. Externally, it is used in the treatment of
  wounds.
  CONTRAINDICATIONS
  Because of its secretion-activating effect, the drug should not
  be administered in the presence of stomach or intestinal
  ulcers.
  PRECAUTIONS AND ADVERSE REACTIONS
  No health hazards or side effects are known in conjunction
  with the proper administration of designated therapeutic
  dosages.
  DOSAGE
  Mode of Administration: Comminuted herb for infusions and
  ^^ other bitter-tasting preparations for internal use.
  Preparation: Tea: Brew 2 to 3 gm drug with 150 ml boiling
  water and strain after 15 minutes; Centaurium Extract:
  extract of 1 part drug to 10 parts water and 1 part 98%
  ethanol steamed till thickened (EB6).
  Liquid extract: 1:1 25% ethanol (V/V) (BHP83).
  Daily Dosage: The average daily dose is 6 gm of drug or 1 to
  2 gm of extract; single dose is 1 gm.

The powdered drug is taken 3 times daily on a wafer with

honey; the infusion is taken 1/2 hour before meals.

The daily dose of extractum Centaurii fluidum is 2 to 5 ml.

Storage: Keep protected from light and moisture in sealed

containers.

LITERATURE

Bishay DW et al., (1978) Planta Med 33:422.

D'Agostino M et al., (1985) Boll Soc Ital Biol Sper 61 (2): 165.

Do T et al., PM 53:580. 1987.'"

% Lacroix R et al., (1973) Tunisie Med 51:327.

Neshta NM et al., (1983) Khim Prir Soed 1:106.

Schimmer O, Mauthner H, Centaurium erythraea RAFN.

Tausendgiildenkraut. In: ZPT 15(5):299-304. 1994.

Schimmer O, Mauthner H, Polymethoxylated xanthones from

the herb of Centaurium erythraea with strong antimutagenic

properties in Salmonella typhimurium. In: PM 62(6):561-564.

1996.

van der Sluis WG, Plant Syst Evol 149:253-286. 1985.

van der Sluis WG et al., (1980) Planta Med 39:268.

van der Sluis WG, PM 41:221-231. 1981.

Further information in:

Hansel R, Keller K, Rimpler H, Schneider G (Hrsg.), Hagers

Handbuch der Pharmazeutischen Praxis, 5. Aufl., Bde 4-6

(Drogen), Springer Verlag Berlin, Heidelberg, New York, 1992-

1994.

Leung AY, Encyclopedia of Common Natural Ingredients Used

in Food Drugs and Cosmetics, John Wiley & Sons Inc., New

York 1980.

Madaus G. Lehrbuch der Biologischen Arzneimittel, Bde 1-3,

Nachdruck, Georg Olms Verlag Hildesheim 1979.

Schulz R, Hansel R, Rationale Phytotherapie, Springer Verlag

Heidelberg 1996.

Steinegger E, Hansel R, Pharmakognosie, 5. Aufl.. Springer

Verlag Heidelberg 1992.

Teuscher E, Biogene Arzneimittel, 5. Aufl., Wiss. Verlagsges.

mbH Stuttgart 1997.

Wagner H, Wiesenauer M, Phytotherapie. Phytopharmaka und

pflanzliche Homoopathika. Fischer-Verlag, Stuttgart, Jena, New

York 1995.

Wichtl M (Hrsg.), Teedrogen, 4. Aufl., Wiss. Verlagsges.

Stuttgart 1997.

Centella asiatica

See Gotu Kola

Centranthus ruber

See Red-Spur Valerian

Cephaelis ipecacuanha

See Ipecac

Ceratonia siliqua

See Carob

Getraria islandica

See Iceland Moss