210 /COLT'S FOOT PDR FOR HERBAL MEDICINESINDICATIONS AND USAGE
COLT'S FOOT FLOWER. HERB, AND ROOT
Unproven Uses: When added to Colt's Foot leaf, the flower,
herb, and root are used to treat rheumatism.COLT'S FOOT LEAF'
Approved by Commission E:- Cough
- Bronchitis
- Inflammation of the mouth and pharynx
Unproven Uses: Colt's Foot leaf is used for inflammation of
the oraFand pharyngeal mucosa. In addition, cigarettes made
of the leaves are used to help cure smoking addiction.CONTRAINDICATIONS
COLT'S FOOT FLOWER. HERB, ROOT. AND LEAF
Administration during pregnancy and while nursing is
contraindicated.PRECAUTIONS AND ADVERSE REACTIONS
COLT'S FOOT FLOWER, HERB, AND ROOT
Because of the possible hepatotoxic and carcinogenic
pyrrolizidine alkaloid content, the administration of the
blossoms should be avoided.COLT'S FOOT LEAF
Colt's Foot leaves may no longer be brought into circulation
in Austria. In Germany, dosages cannot exceed an intake of
10 meg pyrrolizidine alkaloids with l .2-unsaturated necic
parent substances in the form of tea mixtures, and an intake
of l meg in the form of extracts.Because even traces of the alkaloids present some danger,
one should forgo any administration of the drug.DOSAGE
COLT'S FOOT FLOWER, HERB, AND ROOT
Mode of Administration: The drug is used internally through
the use of tea and standardized remedies.Preparation: To prepare a tea, add l .5 to 2.5 gm cut drug to
boiling water, then strain after 5 to 10 minutes.Storage: Protect the drug from light and store it tightly
sealed.COLT'S FOOT LEAF
Mode of Administration: Whole, cut, and powdered drug
used in teas, infusions, extracts, and tinctures.Preparation: To make an infusion, pour hot water over 1.5
to 2.5 gm of drug and allow to draw for 10 minutes. Other
preparations are made as follows: liquid extract: 1:1 with
20% ethanol; extract: 1.1 with 25% ethanol; tincture: 1:5
with 45% ethanol.
Daily Dosage: The total daily dose is 4.5 to 6 gm of drug.
The maximum daily dosage must not be more than 1 meg of
total pyrrolizidine alkaloids with 1.2 unsaturated necine
structure.The tea is given several times a day. The dosage for the
extract is 2 ml 3 times daily; for the tincture, it is 8 ml 3
times daily.Storage: Protect the drug from light and store it tightly
sealed.
LITERATURE
COLT'S FOOT FLOWER, HERB, AND ROOT
Delaveau P et al., (1980) Planta Med 40:49.
Didry N et al., (1982) Ann Pharm Franc 40(1 ):75.
Engalycheva EI et al., (1982) Farmatsiya 31(2):37.
Franz G, PM 17:217. 1969.
Hiller K, Pharmazeutische Bewertung ausgewahlter Teedrogen.
In: DAZ 135(16): 1425-1440. 1995.
Hirono I et al., (1976) Gann 67(1): 125.
Hirono I et al., (1979) J Natl Cane Inst 63(2):469.
Ihrig M, Pyrrolizidinalkaloidhaltige Drogen im Handverkauf? In:
PZ 137(40):3128. 1992.
Kraus C et al., (1985) Planta Med 51(2):89.
Miething H, Steinbach RA, Ermittlung der Freisetzungsraten des
Pyrrolizidinalkaloids Senkirkin in Huflattich-Teegetranken. In:
PZW 135(4): 153. 1990.
PapVeiter CM, Co-occurence of 2-pyrrolidineacetic acid with
four isomeric tussilaginic acids in Arnica species and Tussilago
farfara. In: PM 58(7)94. 1992.
Roder E et al., (1981) Plant Med 43:99.
Roder E, Pyrrolizidinhaltige Arzneipflanzen. In: DAZ
132(45):2427-2435. 1992.
Wagner H, In: Economic and Medicinal Plant Research, Vol. 1,
Academic Press, UK 1985.
Wunderer H, Zentral und peripher wirksame Antitussiva: eine
kritische Ubersicht. In: PZ 142(11):847-852. 1997.
Further information in:
Frohne D, Pfander HJ, Giftpflanzen - Ein Handbuch fur
Apotheker, Toxikologen und Biologen, 4. Aufl., Wiss.
Verlagsges. mbH Stuttgart 1997.
Hansel R, Keller K, Rimpler H, Schneider G (Hrsg.), Hagers
Handbuch der Pharmazeutischen Praxis, 5. Aufl., Bde 4-6
(Drogen): Springer Verlag Berlin, Heidelberg, New York, 1992-
1994.
Madaus G, Lehrbuch der Biologischen Arzneimittel, Bde 1-3,
Nachdruck, Georg Olms Verlag Hildesheim 1979.
Roth L, Daunderer M, Kormann K, Giftpflanzen, Pflanzengifte,- Aufl., Ecomed Fachverlag Landsberg Lech 1993.