PDR for Herbal Medicines

(Barré) #1
HERBAL MONOGRAPHS

Steinegger E, Hansel R, Pharmakognosie, 5. Aufl., Springer
Verlag Heidelberg 1992.
Teuscher E, Lindequist U. Biogene Gifte - Biologie, Chemie,
Pharmakologie, 2. Aufl., Fischer Verlag Stuttgart 1994.
Teuscher E, Biogene Arzneimittel. 5. Aufl., Wiss. Verlagsges.
4t mbH Stuttgart 1997.
Wichtl M (Hrsg.), Teedrogen. 4. Aufl.. Wiss. Verlagsges.
Stuttgart 1997.
COLT'S FOOT LEAF
Delaveau P et al., (1980) Planta Med 40:49.
Didry N et al., (1982) Ann Pharm Franc 40(1 ):75.
Engalycheva El et al., (1982) Farmatsiya 3l(2):37.
Franz G, PM 17:217. 1969.
Hiller K. Pharmazeutische Bewertung ausgewahlter Teedrogen.
In: DAZ 135(16): 1425-1440. 1995.
Hirono I et al., (1976) Gann 67(1): 125.
Hirono I et al., (1979) J Natl Cane Inst 63(2):469.
Ihrig M, Pyrrolizidinalkaloidhaltige Drogen im Handverkauf? In:
PZ 137(40):3128. 1992.
Kraus C et al., (1985) Planta Med 51(2):89.
Miething H, Steinbach RA. Ermittlung der Freisetzungsraten des
%" Pyrrolizidinalkaloids Senkirkin in Huflattich-Teegetriinken. In:
PZW 135(4): 153. 1990.
PapVeiter CM, Co-occurence of 2-pyrrolidineacetic acid with
four isomeric tussilaginic acids in Arnica species and Tussilago
farfara. In: PM 58(7)94. 1992.
Roder E et al., (1981) Plant Med 43:99.
Roder E, Pyrrolizidinhaltige Arzneipflanzen. In: DAZ
132(45):2427-2435. 1992.
Wagner H, In: Economic and Medicinal Plant Research, Vol. 1,
Academic Press, UK 1985.
Wunderer H, Zentral und peripher wirksame Antitussiva: eine
kritische Ubersicht. In: PZ 142(11):847-852. 1997.
Further information in:
Frohne D, Pfander HJ, Giftpflanzen - Ein Handbuch fiir
Apotheker, Toxikologen und Biologen, 4. Aufl., Wiss.
Verlagsges. mbH Stuttgart 1997.
Hansel R, Keller K, Rimpler H, Schneider G (Hrsg.), Hagers
Handbuch der Pharmazeutischen Praxis, 5. Aufl., Bde 4-6
(Drogen): Springer Verlag Berlin, Heidelberg, New York, 1992-
jfe 1994.


Madaus G, Lehrbuch der Biologischen Arzneimittel, Bde 1-3,
Nachdruck, Georg Olms Verlag Hildesheim 1979.
Roth L, Daunderer M, Kormann K, Giftpflanzen, Pflanzengifte,


  1. Aufl., Ecomed Fachverlag Landsberg Lech 1993.
    Steinegger E, Hansel R, Pharmakognosie, 5. Aufl., Springer
    Verlag Heidelberg 1992.
    Teuscher E, Lindequist U, Biogene Gifte - Biologie, Chemie,
    Pharmakologie, 2. Aufl., Fischer Verlag Stuttgart 1994.


COLUMBINE/211

Teuscher E, Biogene Arzneimittel, 5. Aufl., Wiss. Verlagsges.
mbH Stuttgart 1997.
Wichtl M (Hrsg.), Teedrogen, 4. Aufl., Wiss. Verlagsges.
Stuttgart 1997.

Columbine
Aquilegia vulgaris

DESCRIPTION
Medicinal Parts: The medicinal parts are the stems and
leaves, the aerial parts gathered and dried in flowering
season, and the seeds and preparations of the whole plant
also gathered in flowering season.

Flower and Fruit: The long-stemmed flowers are terminal,
hanging, and either dark blue, dark violet, pink or white. The
5 sepals spread like petals. They are broadly ovate, and end
in a blunt, green tip. The 5 petals are hood-shaped with long,
inwardly hooked spurs. There are numerous stamens and
usually 5 ovaries. The follicle is oblong, erect and glandular-
downy. The seeds are glossy black, oval, 2.2 to 2.5 cm long
by 1.5 cm wide. They are thick, blunt-tipped and anatropous.
The raphe forms a distinct line on the side of the plant.

Leaves, Stem and Root: The 30- to 60-cm high plant has a
many-headed, light brown and branched rhizome. The stems
are erect and usually branched. They are glabrous or soft-
haired. The basal leaves are long-petioled and trifoliate. The
leaflets are wedge-shaped to ovoid, blunt, irregularly crenate
to serrate, and bluntly lobed. The underside of the leaves are
usually light green and pubescent. The cauline leaves are
smaller than the basal leaves and simpler. The highest leaves
are usually made up of a few elongate-ovate, entire-margined
lobes.

Habitat: Columbine is indigenous to central and southern
Europe and is also found in the eastern U.S. and Asia.

Production: Columbine herb is the complete aerial part of
Aquilegia vulgaris harvested while in flower and dried.

Other Names: Culverwort, Capon's Feather, Culver Key

ACTIONS AND PHARMACOLOGY
COMPOUNDS
Cyanogenic glycosides: trigloquinine, dhurrin (presumably
only traces)

EFFECTS
It is not known which constituents are responsible for the
herb's effects. The cyanogenic glycoside trigloquinine could
possibly be of toxicological interest but is probably only
present in traces.
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