HERBAL MONOGRAPHS CRANESBILL/233Middleton E, Drzewiecki G, (1984) Biochem. Pharmacol.
33:3333.
Thieme H, Winkler HJ, (1971) Pharmazie 7:434.
Further information in:
4Qf Hansel R, Keller K, Rimpler H, Schneider G (Hrsg.), Hagers
Handbuch der Pharmazeutischen Praxis, 5. Aufl., Bde 4-6
(Drogen), Springer Verlag Berlin, Heidelberg, New York, 1992-
1994.
Madaus G, Lehrbuch der Biologischen Arzneimittel. Bde 1-3,
Nachdruck, Georg Olms Verlag Hildesheim 1979.
Steinegger E, Hansel R, Pharmakognosie, 5. Aufl.. Springer
Verlag Heidelberg 1992.
Teuscher E, Lindequist U. Biogene Gifte - Biologic Chemie,
Pharmakoiogie, 2. Aufl., Fischer Verlag Stuttgart 1994.
Teuscher E, Biogene Arzneimittel, 5. Aufl., Wiss. Verlagsges.
Stuttgart 1997.
Wichtl M (Hrsg.), Teedrogen, 4.'Aufl.. Wiss. Verlagsges.
Stuttgart 1997.
COWSLIP ROOT
Biiechi S, Antivirale Saponine, pharmakologische und klinische
£ Untersuchungen. In: DAZ 136(2):89-98. 1996.
Busse WW et al., (1984) J All Clin Immunol. 73:801.
Calis I, Yuruker A, Riiegger H. Wright AD. Sticher O,
Triterpene saponins from Primula veris ssp. macrocalyx and
Primula elatiro ssp. meyeri. In: JNP 55:1299-1306. 1992.
Grecu VL, Cucu V, (1975) Planta Med 25:247.
Karl C et al., (1981) Planta Med 41:96.
Middleton E, Drzewiecki G, (1984) Biochem. Pharmacol.
33:3333.
Thieme H, Winkler HJ, (1971) Pharmazie 7:434.
Wagner H et al., Radix-Primulae-Extrakte. HPLC-Analyse. In:
DAZ 126:1489-1493. 1986.
Further information in:
Hansel R, Keller K, Rimpler H, Schneider G (Hrsg.), Hagers
Handbuch der Pharmazeutischen Praxis, 5. Aufl., Bde 4-6
(Drogen), Springer Verlag Berlin, Heidelberg, New York, 1992-
1994.£' Madaus G, Lehrbuch der Biologischen Arzneimittel, Bde 1-3,
Nachdruck, Georg Olms Verlag Hildesheim 1979.
Steinegger E, Hansel R, Pharmakognosie, 5. Aufl., Springer
Verlag Heidelberg 1992.
Teuscher E, Biogene Arzneimittel, 5. Aufl., Wiss. Verlagsges.
Stuttgart 1997.
Wichtl M (Hrsg.), Teedrogen, 4. Aufl., Wiss. Verlagsges.
Stuttgart 1997.
Cranesbill
Geranium maculatumDESCRIPTION
Medicinal Parts: The medicinal parts are the plant's dried
rhizome and the leaves.Flower and Fruit: The inflorescence is a terminal, cymose
umbel. The flowers are radial with the structures arranged in
fives with a 2.5 to 4 cm diameter. There are 5 free, pubescent
sepals, 5 free purple petals and 10 stamens. The ovary is
formed from 5 carpels, which are fused to the sides of the
central column with their long awns. The fruit is a
schizocarp, which breaks up into 5 mericarps with beak-like
extensions and 1 seed each.Leaves, Stem and Root: The herbaceous perennial grows
upright, rising to 60 cm high. The leaves are opposite, in
fives with cuneiform lobes and whitish-green spots when
older. Leaves growing from the rhizome are large with long,
pubescent petioles: those growing from the trunk have short
petioles; stipules are present. The stem is upright, green,
pubescent and dichotomously branched. The rhizome is
thick, cylindrical and branched.Habitat: The plant is found throughout Europe, but also in
North America from Newfoundland to Manitoba and as far
south as Georgia and Missouri. It grows in shady and moist
ground in mixed and deciduous forests.Production: American Cranesbill herb is the dried aerial
herb of Geranium maculatum harvested during the flowering
season. American Cranesbill root is the dried rhizome of
Geranium maculatum, which is collected in late summer and
autumn.Other Names: Alumroot, Crowfoot, Geranium, Spotted
Cranesbill, Spotted Geranium, Storksbill, Wild CranesbillACTIONS AND PHARMACOLOGY
COMPOUNDS: CRANESBILL HERB
Tannins (30%): gallotanninsCOMPOUNDS: CRANESBILL ROOT
Tannins (10 to 28%): gallotanninsEFFECTS
The tannins give the drug astringent, hemostyptic and tonic
properties.
INDICATIONS AND USAGE
Unproven Uses: Folk medicine indications have included
hemorrhoids, duodenal ulcers, diarrhea, metrorrhagia, heavy
menstruation and dysmenorrhea. Efficacy for these internal
use indications has not yet been proven.