PDR for Herbal Medicines

HERBAL MONOGRAPHS GAMBOGE/ 325

DOSAGE

Mode of Administration: Whole and powdered drug for

internal use.

, Preparation: Tincture: 200 g drug (pounded), 50 g cut

cinnamon to 1 liter 45% ethanol, macerated (BP88)

Daily Dosage: 0.5 to 2 g drug; Catechu Tincture: 2.5 to 5 ml

LITERATURE

Balz JP. Das NP. Uncaria elliptica a major source of rutin.

Planta Med, 25:174-7, 1979 Jun.

Blaschek W. Hansel R. Keller K. Reichling J, Rimpler G,

Schneider G (Eds), Hagers Handbuch der Pharmazeutischen

Praxis. Folgeb nde 1 und 2. Drogen A-Z. Springer. Berlin,

Heidelberg 1998.

Chang CC. Tung LH. Chen RR. Chiueh CC, A study on the

antihypertensive action of uncarine A, an alkaloid of Uncaria

formosana used in Chinese herb medicine. Taiwan I Hsueh Hui

Tsa Chih. 25:61-9, 1979 Feb.

Chang P. Koh YK. Geh SL. Soepadmo E. Goh SH. Wong AK,

Cardiovascular effects in the rat of dihydrocorynantheine

isolated from Uncaria callophylla. J Ethnopharmacol, 25:213-5,

1989 Apr.

Endo K. Oshima Y, Kikuchi H. Koshihara Y, Hikino H,

•r Hypotensive principles of Uncaria hooks. Planta Med, 25:188-

90, 1983 Nov.

Haginiwa J. Sakai S. Takahashi K, Taguchi M, Shujiro S,

Studies of plants containing indole alkaloids. I. Alkaloids in

Uncaria genus. Yakugaku Zasshi, 25:575-8, 1971 May.

Law KH. Das NP, Initiation and maintenance of callus tissue

culture of Uncaria elliptica for flavonoid production. Prog Clin

Biol Res. 25:67-70, 1988.

Lin CC. Lin JM, Chiu HF, Studies on folk medicine 'thang-

kau-tin' from Taiwan. (I). The anti-inflammatory and liver-

protective effect. Am J Chin Med, 57:37-50, 1992.

Lin JM, Lin CC, Chen MF, Ujiie T, Takada A, Studies on

Taiwan folk medicine, thang-kau-tin (II): Measurement of active

oxygen scavenging activity using an ESR technique. Am J Chin

Med, 57:43-51. 1995.

Mimaki Y, Toshimizu N, Yamada K, Sashida Y, Anti-

convulsion effects of choto-san and chotoko (Uncariae Uncis

cam Ramlus) in mice, and identification of the active principles.

Yakugaku Zasshi, 57:1011-21, 1997 Dec.

ML Yamanaka E, Kimizuka Y, Aimi N, Sakai S, Haginiwa J,
Studies of plants containing indole alkaloids. IX. Quantitative
analysis of tertiary alkaloids in various parts of Uncaria
rhynchophylla MIQ. Yakugaku Zasshi, 25:1028-33, 1983 Oct.
Yano S. Horiuchi H, Horie S, Aimi N, Sakai S, Watanabe K,
Alkaloids from the leaves of Uncaria homomalla. Planta Med,
57:749-52, 1980 Sep.
Yano S, Horiuchi H, Horie S, Aimi N, Sakai S, Watanabe K,
Alkaloids of Uncaria pterppoda. Isolation and structures of

pteropodine and isopteropodine. J Chem Soc Perkin 1, 57:2245-

9, 1966.

Yano S, Horiuchi H, Horie S, Aimi N, Sakai S, Watanabe K,

Ca2+ channel blocking effects of hirsutine, an indole alkaloid

from Uncaria genus, in the isolated rat aorta. Planta Med,

57:403-5, 1991 Oct.

Yano S, Horiuchi H, Horie S, Aimi N, Sakai S, Watanabe K,

Gambirine, a new indole alkaloid from Uncaria gambier roxb.

Tetrahedron Lett, 57:1571-4, 1967 Apr.

Yano S, Horiuchi H, Horie S, Aimi N, Sakai S, Watanabe K,

Studies on flavonoid metabolism. Biosynthesis of (+)-

14Ccatechin by the plant Uncaria gambir Roxb. Biochem J,

57:73-7, 1967 Oct.

Yano S, Horiuchi H, Horie S, Aimi N, Sakai S, Watanabe K,

Studies on Uncaria alkaloid. XXI. Separation of rhynchophylline

and corynoxeine (author's transl.). Yakugaku Zasshi, 57:758-9,

1975 Jun.

Yano S, Horiuchi H, Horie S, Aimi N, Sakai S. Watanabe K,

The antihypertensive effect of Uncaria rhynchophylla in

essential hypertension (author's trans!.). Taiwan I Hsueh Hui

Tsa Chih, 57:749-52, 1980 Sep.

Zhu M, Bowery NG, Greengrass PM, Phillipson JD,

Application of radioligand receptor binding assays in the search

for CNS active principles from Chinese medicinal plants. J

Ethnopharmacol, 57:153-64, 1996 Nov.

Gamboge

Garcinia hanburyi

DESCRIPTION

Medicinal Parts: The medicinal part of the tree is the resin

extracted from the plant.

Leaves, Stem and Root: The tree grows to about 15 m and

has a diameter of about 30 cm. The bark is usually in the

form of cylindrical sticks, deep orange-brown and opaque.

The transverse fracture is smooth and almost conchoidal.

Characteristics: The taste is innocuous at first, then becomes

very acrid and causes an unpleasant stinging sensation

shortly after being placed in the mourn. The powder is highly

sternutatory.

Habitat: The plant is indigenous to Indochina and Sri Lanka.

Production: Gamboge is the gum-resin from the trunk of

Garcinia hanburyi harvested from trees that are at least ten

years old.

Other Names: Camboge, Gutta Cambodia, Gutta Gamba,

Gummigutta, Tom Rong, Gambodia