PDR for Herbal Medicines

(Barré) #1
456 /LADY'S BEDSTRAW PDR FOR HERBAL MEDICINES

Corrigan D et al., (1978) Phytochemistry 17:1131.
Hansel R. Keller K, Rimpler H, Schneider G (Hrsg.), Hagers
Handbuch der Pharmazeutischen Praxis, 5. Aufl., Bde 4-6
(Drogen). Springer Verlag Berlin, Heidelberg, New York, 1992-
1994.
Mathe-feet al., (1982) Planta Med 45:158.
Raynaud J. Mnajed H, (1972) C R Acad Sci Paris 274:1746.
Wichtl M (Hrsg.), Teedrogen. 4. Aufl., Wiss. Verlagsges.
Stuttgart 1997.

Lady's Mantle


Alchemilla vulgaris

DESCRIPTION
Medicinal Parts: The medicinal part is the herb collected in
the flowering season and dried.

Flower and Fruit: The plant has inflorescences of small,
insignificant, yellow-green, many-flowered cymes. The peri-
anth is 4-leaved. The flower has 4 stamens, 1 ovary and an
inferior style. The fruit is enclosed in the calyx. The flowers
are infertile.

Leaves, Stem and Root: Alchemilla vulgaris is a hardy, half-
rosette shrub, which grows from 30 to 50 cm. It has a
branched stem, which is villous to glabrous. The basal leaves
are round, 7- to 9-lobed (dew cup); cauline leaves are short-
petioled to sessile, 5- to 7-lobed, crenate or serrate and
villous. Even the older leaves remain more or less folded.

Characteristics: Lady's Mantle is odorless and has an
astringent taste.

Habitat: The plant gfovfs in the Northern Hemisphere from
North America, Greenland and Europe to the Mediterranean
and Iceland; and Asia from the Caucasus and the Himalayas
to Siberia.

Production: Lady's Mantle herb consists of the fresh or dried
above-ground parts of Alchemilla vulgaris gathered at
flowering time, as well as its preparations. It is produced
mostly through cultivation.

Other Names: Bear's Foot, Leontopodium, Lion's Foot,
Nine Hooks, Stellaria

ACTIONS AND PHARMACOLOGY
COMPOUNDS
Bitter principles


Flavonoids


Tannins


EFFECTS
Lady's Mantle herb has astringent properties, due to the
presence of tannins. It has also been shown to inhibit tumor
growth. In mice the total retardation of breast neoplasm-
induced tumors was achieved using agrimoniin and the
average life expectancy of the animals was increased. An
extract of the drug hinders the enzymes elastase, trypsin and
a-chymotrysin.
INDICATIONS AND USAGE
Approved by Commission E:


  • Diarrhea
    Unproven Uses: Lady's Mantle is used for mild and non-
    specific diarrhea and gastrointestinal disorders.


In folk medicine the drug is used internally for menopausal
complaints, dysmenorrhea, gastrointestinal disorders, and as
a gargle for mouth and throat inflammation. Externally, it is
used for ulcers, eczema, skin rashes and as an additive in
baths for the treatment of lower-abdominal ailments.
Homeopathic Uses: Alchemilla vulgaris is used for Ieucor-
rhea and for chronic diarrhea resulting from liver disease.
PRECAUTIONS AND ADVERSE REACTIONS
No health hazards or side effects are known in conjunction
with the proper administration of designated therapeutic
dosages.
DOSAGE
Mode of Administration: Lady's Mantle herb is administered
as a cut herb for infusions and decoctions, as well as other
galenic preparations for internal use.
Preparation: Tea: 2 to 4 gm drug to 150 ml hot water left to
draw for 10 minutes. .Prepare a fresh batch every day.
Daily Dosage: Lady's Mantle herb is administered in 2 to 4
gm single doses as an infusion; the average daily dose is 5 to
10 gm of herb. The tea is taken 3 times daily between meals.
Homeopathic Dosage: 5 drops, 1 tablet, 10 globules, every
30 to 60 minutes (acute) and 1 to 3 times daily (chronic);
Parenterally: 1 to 2 ml 3 times daily sc; Ointment: Apply 1 to
2 times daily (HAB1).
LITERATURE
Dome AJ et al., PH 25:65-68. 1986.
Filfpek J, The effect of Alchemilla xanthochlora on lipid
peroxidation and superoxide anion scavenging acticity. In: PA
47:717-718. 1992.
Geiger C, Rimpler H, PM 56:585-586. 1990.
Geiger C. Ellagitannine aus Alchemilla xanthochlora
ROTHMALER und Potentilla erecta (L.) RAEUSCHEL.
Beitrage zur Analytik und Strukturaufklarung. In: Dissertation
Universitat Freiburg. 1990.
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