592/PIMPINELLA PDR FOR HERBAL MEDICINESEFFECTS: PIMPINELLA HERB
No information is available.COMPOUNDS: PIMPINELLA ROOT
Volatile oil (0.05 to 0.7%): chief components- trans-epoxy-
pseudo-isoeugenol (20-57%), additionally pregeijeren
(10%), geijerene (3%), beta-bisabolene, germacrenes A to D,
1,4-dimethyl azuleneFurocoumarins (1.2-2.3%): including among others bergap-
tene, isopimpinellin, pimpinellin, isobergapten, sphondineHydroxycoumarins: umbelliferone, scopoletinCaffeic acid esters: including among others, chlorogenic
acidPolyynes: including trideca-2,8,10-trien-4,6-diine; trideca-
2,8-dien-4,6-diin-10-oleEFFECTS: PIMPINELLA ROOT
The drug contains essential oil. The efficacy of the drug as a
flushing-out therapy in bacterial infections of the urinary
tract seems plausible. The expectorant effect has not been
proven.
INDICATIONS AND USAGE
PIMPINELLA HERB
Preparations of Pimpinella herb are used internally for lung
ailments and to stimulate gastrointestinal activity. The herb
is used externally for varicose veins.PIMPINELLA ROOT
Approved by Commission E:- Cough/bronchitis
Preparations of the root are also used for colds, chills and
catarrh of the yppef- respiratory tract.Unproven Uses: In folk medicine, it is used internally for
disorders of the urinary organs, inflammation of the bladder
and kidney, bladder and kidney stones, and edema. It is also
used as flushing-out therapy in bacterial inflammation of the
efferent urinary tract. Externally, it is used for inflammation
of the oral and pharyngeal mucous membrane and as a bath
additive for poorly healing wounds.•Homeopathic Uses: Homeopathic uses include febrile states
and spinal pain. Efficacy of the flushing-out therapy seems
plausible, efficacy for the other indications has not been
sufficiently proven.
PRECAUTIONS AND ADVERSE REACTIONS
PIMPINELLA HERB
No health hazards or side effects are known in conjunction
with the proper administration of designated therapeutic
dosages.
PIMPINELLA ROOT
No health hazards or side effects are known in conjunction
with the proper administration of designated therapeutic
dosages. Photosensitivity may occur in light-skinned
individuals.
DOSAGE
PIMPINELLA ROOT
Mode of Administration: Pimpinella root is administered as a
tincture (Tinctura Pimpinellae) and as a comminuted herb for
teas and other galenic preparations for internal use.Daily Dosage: 6 to 12 g drug for infusions or 6 to 15 ml
pimpernel tincture (1:5).Folk medicine — Add freshly cut drug to cold water and
bring to the boil, use as a gargle and as a bath additive.
Infusion — 3 to 10 g; 1 cup 3 to 4 times daily (sweetened
with honey).
Gargle tincture — 30 drops in a glass of water.
For coughs — 5 to 10 drops on a sugar lump.
Homeopathic Dosage: 5 drops, 1 tablet or 10 globules every
30 to 60 minutes (acute) or 1 to 3 times daily (chronic);
parenterally: 1 to 2 ml sc; acute: 3 times daily; chronic: once
a day (HAB1).
LITERATURE
PIMPINELLA HERB
Bohn IU, Pimpinella saxifraga und Pimpinella major-Kleine und
Gro£e Bibemeile. In: ZPT 12(3):98. 1991.
Kubeczka KH, Formacek V, New Constituents from the
Essential Oils of Pimpinella. In: Brunke EJ (Ed.) Progress in
Essential Oil Research, Walter de Gruyter & Co, Berlin 1986.
1986.
Martin R et al., (1985) Planta Med 51(3): 198.
Reichling J, Martin R, Pseudoisoeugenole - eine Gruppe
seltener Phenylpropanoide im Genus Pimpinella: Biosynthese
unfd biologische Wirkung. In: PZW 136(5/6)225. 1991.
Further information in:
Hansel R, Keller K, Rimpler H, Schneider G (Hrsg.), Hagers
Handbuch der Pharmazeutischen Praxis, 5. Aufl., Bde 4-6
(Drogen), Springer Verlag Berlin, Heidelberg, New York, 1992-
1994.
Madaus G, Lehrbuch der Biologischen Arzneimittel, Bde 1-3,
Nachdruck, Georg Olms Verlag Hildesheim 1979.
PIMPINELLA ROOT
Bohn IU, Pimpinella saxifraga und Pimpinella major-Kleine und
Grope Bibernelle. In: ZPT 12(3):98. 1991.
Kubeczka KH, Formacek V, New Constituents from the
Essential Oils of Pimpinella. In: Brunke EJ (Ed.) Progress in
Essential Oil Research, Walter de Gruyter & Co, Berlin 1986.
Martin R et al., (1985) Planta Med 51(3): 198.