608/POPLAR PDR FOR HERBAL MEDICINES
In Populus tremula (leaf 3%, bark 2%) chief components:
salicin, tremulacin, salicortin including as well as salirepo-
side, populin, tremuloidin
EFFECTS
Poplar bark and leaves have antiphlogistic, analgesic,
antibacterial and spasmolytic effects.
The salicylate acid derivatives and flavonoids are responsible
for the antiphlogistic, analgesic, spasmolytic and antibacteri-
al characteristics of the drug. The beneficial effect in
micturition complaints due to prostate hypertrophy may be
due to the content of zinc lignans in the drug.
COMPOUNDS: POPLAR LEAF BUDS
Flavonoids: (particularly in the glutinous coating of the
buds, also yielding propolis) including chrysin, tectochrysin,
galengine, izalpinine, galangin-3-methyl ether, kaempferol-
3-methyl ether, pinocembrin, pinocembrin-7-methyl ether,
apigenin
Glycosides and esters yielding salicylic acid: including
salicin, populin
Volatile oil: chief components alpha- and beta-caryophyllene
EFFECTS: POPLAR LEAF BUDS
Poplar buds have antiphlogistic, antibacterial and wound
healing effects.
INDICATIONS
POPLAR BARK AND LEAVES
Unproven Uses: Poplar bark and leaves are used for pain and
rheumatism therapy; and in micturition complaints due to
prostate hypertrophy.
POPLAR LEAF BUDS
Approved by Commission E:
- Hemorrhoids
- Wounds and bums
Unproven Uses: Poplar buds are used for superficial skin
injuries, external hemorrhoids, frostbite and sunburn.
CONTRAINDICATIONS
POPLAR BARK AND LEAVES
Contraindicated in cases of hypersensitivity to salicylates.
POPLAR LEAF BUDS
Contraindicated in cases of hypersensitivity to salicylates,
propolis and balsam of Peru, which may be a componant in
commercially available ointments.
PRECAUTIONS
POPLAR BARK AND LEAVES
No health hazards or side effects are known in conjunction
with the proper administration of designated therapeutic
dosages.
POPLAR LEAF BUDS
No health hazards are known in conjunction with the proper
administration of designated therapeutic dosages. External
administration of the drug occasionally leads to allergic skin
reactions.
DOSAGE
POPLAR BARK AND LEAVES
Mode of Administration: Poplar leaves are available in crude
form as well as galenic preparations for internal use. Poplar
bark is only available in compounded preparations.
Daily Dosage: 10 gm of drug
POPLAR LEAF BUDS
Mode of Administration: Poplar buds are available in semi-
solid preparations for application to the skin.
How Supplied: Semi-solid preparations equivalent to 20% to
30% of drug.
Daily Dosage: Externally, 5 gm drug.
LITERATURE
POPLAR BARK AND LEAVES
Anonym. Phytotherapie: Pflanzliche Antirheumatika - was
bringen sie? In: DAZ 136(45):4012-4015. 1996.
Jossang A et al., Cinnamrutinoses A and B, glycosides from
Populus tremula. In: PH 35(2):547. 1994.
Picard S et al., Isolation of a new phenolic compound from
leaves of Populus deltoides. In: JNP 57(6):808-810. 1994.
Thieme H, Benecke R, (1969) Pharmazie 24:567.
Vonkruedener S et al., Effects of extracts from Populus tremula
L., Solidago virgaurea L. and Fraxinus excelsior L. on various
myeloperoxidase systems. In: Arzneim Forsch 46(8): 809-814.
1996.
Further information in:
Fenaroli's Handbook of Flavor Ingredients, Vol. 1. 2nd Ed.
Pub. CRC Press Boca Raton 1975.
Hegnauer R, Chemotaxonomie der Pflanzen, Bde 1-11,
Birkhauser Verlag Basel, Boston, Berlin 1962-1997.
Kern W, List PH, Horhammer L (Hrsg.), Hagers Handbuch der
Pharmazeutischen Praxis, 4. Aufl., Bde. 1-8, Springer Verlag
Berlin, Heidelberg, New York, 1969.
Leung AY, Encyclopedia of Common Natural Ingredients Used
in Food, Drugs and Cosmetics, John Wiley & Sons Inc., New
York 1980.
Madaus G, Lehrbuch der Biologischen Arzneimittel, Bde 1-3,
Nachdruck, Georg Olms Verlag Hildesheim 1979.
Wagner H, Wiesenauer M, Phytotherapie. Phytopharmaka und
pflanzliche Homoopathika, Fischer-Verlag, Stuttgart, Jena, New
York 1995.
POPLAR LEAF BUDS
Anonym, Phytotherapie: Pflanzliche Antirheumatika - was
bringen sie? In: DAZ 136(45):4012-4015. 1996.
