PDR for Herbal Medicines

(Barré) #1
HERBAL MONOGRAPHS PURPLE GROMWELL (YING Z1CAO) /619

EFFECTS
As well as amaroids (cucurbitacin), the drug contains delta-
7-sterols, which are similar in conformation to the dihydros-
testerone. Cucurbitacin has anthelmintic properties.

There are no pharmacological studies that substantiate the
empirically documented clinical efficacy; the empirical
evidence indicates efficacy for prostate hyperplasia. Pump-
kin is also antiphlogistic and antioxidative.
INDICATIONS AND USAGE
Approved by Commission E:


  • Irritable bladder

  • Prostate complaints
    Unproven Uses: Pumpkin is used for irritable bladder,
    micturition problems accompanying prostate adenoma stages
    I to II. This medication relieves only the difficulties
    associated with an enlarged prostate without reducing the
    enlargement. Medical supervision is essential.
    In folk medicine, it is also used for kidney inflammation,
    intestinal parasites, particularly tape worm, and vulnary.
    PRECAUTIONS AND ADVERSE REACTIONS v
    Health risks or side effects following the proper administra-
    tion of designated therapeutic dosages are not recorded.
    DOSAGE
    Mode of Administration: Whole and coarsely ground seed
    and other galenic preparations are for internal use.


Daily Dosage: The average daily dose is 10 gm of ground
seeds; I to 2 heaping dessert spoons with liquid in the
mornings and evenings.
Storage: It should be protected from light and moisture.
LITERATURE
Anonym, Welche Bedeutung haben pflanzliche Prostatamittel.
In: DAZ 133(9):720. 1993.
Koch E, (1995) Pharmakologie und Wirkmechanismen von
Extrakten aus Sabalfruchten (Sabal fructus), Brennesselwurzeln
(Urticae radix) und Ktirbissamen (Cucurbitae peponis semen)
bei der Behandlung der benignen Prostatahyperplasie. In: Loew
D, Rietbrock N (Hrsg.) Phytopharmaka in Forschung und
klinischer Anwendung. Steinkopff Verlag, Darmstadt, S 57-79.
Miersch WDE, Benigne Prostatahyperplasie. In: DAZ
133(29):2653. 1993.
Nahxstedt A, (1993) Pflanzliche Urologica - eine kritische
Ubersicht. Pharm Z 138:1439-1450.
Schabort JC, (1978) Phytochemistry 17:1062.

Schiebel-Schlosser G., Kiirbiskerne starken die Blasenfunktion.
In: PTA 4(11):552. 1990.


Schilcher H, Moglichkeiten und Grenzen der Phytotherapie am
Beispiel pflanzlicher Urologika. Urologe [B] 27 (1987), 316-319


Schilcher H, (1987a) Pflanzliche Diuretika. Urologe [B] 27:215-
222; (1987b)n Moglichkeiten und Grenzen der Phytotherapie am
Beispiel pflanzlicher Urologika. Urologe [B] 27:316-319.
Schilcher H, Boesel R, Effenberger ST Segebrecht S, Neuere
Untersuchungsergebnisse mit aquaretisch, antibakteriell und
prostatotrop wirksamen Arzneipflanzen. In: ZPT 10(3):77. 1989.
Schilcher H, Dunzendorfer U, Ascali F, Dekta-7-Sterole, das
prostatatrope Wirkprinzip des Kiirbis? In: Urologe (B) 27:316-




    1. Tewary JP, Srivasta MC, (1968) J Pharm Sci 57:328.
      Further information in: • ...
      Hansel R, Keller K. Rimpler H, Schneider G (Hrsg.), Hagers
      Handbuch der Pharmazeutischen Praxis, 5. Aufl., Bde 4-6
      (Drogen), Springer Verlag Berlin, Heidelberg, New York, 1992-




  1. Madaus G, Lehrbuch der Biologischen Arzneimittel, Bde 1-3,
    Nachdruck, Georg Olms Verlag Hildesheim 1979.
    Oliver-Bever B (Ed.), Medicinal Plants of Tropical West Africa,
    Cambridge University Press, Cambridge, London 1986.
    Steinegger E, Hansel R, Pharmakognosie, 5. Aufl., Springer
    Verlag Heidelberg 1992.
    Teuscher E, Biogene Arzneimittel, 5. Aufl.*, Wiss. Verlagsges.
    mbH Stuttgart 1997.
    Wagner H, Wiesenauer M, Phytotherapie. Phytopharmaka und
    pflanzliche Homoopathika, Fischer-Verlag, Stuttgart, Jena, New
    York 1995.
    Wichtl M (Hrsg.), Teedrogen, 4. Aufl., Wiss. Verlagsges.
    Stuttgart 1997.




Punica granatum
See Pomegranate

Purple Gromwell


(Ying Zicao)
Lithospermum erytrorhizon
DESCRIPTION
Medicinal Parts: The medicinal part of the plant is the root,
which is dried.
Flower and Fruit: The radial flowers are in axillary or apical
racemes. The calyx has up to 5 tips, and the sepals are fused.
The petals are white and also fused. The corolla tube is
approximately 4 mm long. The diameter of the corolla is
approximately 4 mm. There are 5 stamens and one superior,
2-carpeled, 4-chambered ovary. The fruit is a glossy nutlet,
approximately 3 mm long, ovoid and gray-white.
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