Wilcoxon matched pairs signed ranks test

1. Take the difference for each pair of readings

Patients 1 2 3 4 5 6 7 8 9 10

Drug score 19 11 14 17 23 11 15 19 11 8

Placebo

score

22 18 17 19 22 12 14 11 19 7

difference - 3 - 7 - 3 - 2 1 - 1 1 8 - 8 1