Increased fluid retention may be due to inappropriate anti-
diuretic hormone (ADH, a pituitary hormone) secretion. Inappropriate ADH is associated with many drugs and diseases, including disorders affecting the central nervous system.
In some cases, voluntary excessivewater intake may also lead todilutional hyponatremia.Symptoms of hyponatremia include headache, nausea, vomiting,
muscle cramps, fatigue, disorientation, and fainting.Complications of severe and rapidly developing hyponatremia
may include cerebral edema (swelling of the brain), seizures, coma, and brain damage. Acute or severe hyponatremia may be fatalwithout prompt and appropriate medical treatment. Exercise and Hyponatremia
Read about this underAthlete Considerationson page166.Disease Prevention (Salt Reduction) Gastric Cancer
Studies in Asian countries indicate that high intakes of salted,
smoked, and pickled foods increase the risk of stomach cancer.Although high in salt, these foods may also contain carcinogens
such as nitrosamines.Populations with high intakes ofsalted foods tend to have lowintakes of fruits and vegetables, which are also associated with increased risk of gastric cancer.The risk of developing stomach cancer is increased by chronic
inflammation of the stomach and infection by the bacteria, Helicobacter pylori. High concentrations of salt may damage the
cells lining the stomach, increasing the risk ofH. pyloriinfection.Kidney Stones
Most kidney stones contain calcium. Elevated urinary calcium
increases the risk of developing calcium stones.Increased dietary salt increases urinary calcium excretion, and
may contribute to calcium-containing kidney stones.Salt restriction reduces urinary calcium in those with a tendencyto form calcium stones; a diet low in salt and animal protein decreases stone recurrence more effectively than a low-calcium diet. Osteoporosis
Increased salt intake increases the urinary excretion of calcium. Each 2.3-gram increment of sodium (5.8 grams of salt) excreted
by the kidney draws about 30 milligrams of calcium into the urine.Studies are needed to determine whether decreasing salt intake
improves bone mineral density or reduces fracture risk.Read more about osteoporosis under calcium in the free
supplement to this book available at: http://roadbikerider.com/nutritionforsportssupplement.htm.Disease Treatment (Salt Reduction) Hypertension (High Blood Pressure)
Reduction of dietary salt has been advocated as a means to
prevent and treat hypertension for more than 30 years.The benefits of dietary salt reduction are controversial. The most recent meta-analysis of data pooled from more than
100 studies found reducing salt intake by about 6 grams per day lowered blood pressure by 3.9/1.9 millimeters mercury (mm Hg,systolic BP/diastolic BP) in those with high blood pressure. Even greater reductions in salt intakelowered blood pressure by only1.2/0.3 mm Hg in those with normal blood pressure.Clinicians have questioned the value of such modest blood
pressure reductions in hypertensivepatients, although some studiesshow that these amounts could be important.Nutrition for Sports, Essentials of 165