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There are two methods nurses can use to calculate the desired dose. These are
the formula method or the ratio-proportion method. Either method will produce
same result. When applying either method, make sure that all the terms are in
the same units before calculating the desired dose. For example, the medication
order might be in grams and the dose on hand might be in milligrams. The nurse
will need to convert the grams to milligrams before calculating the desired dose
to give. Always convert to the unit of the “have” dose.
The formula method uses the following formula to determine the correct dose.

×V=A Quantity (Desired dose divided by dose you have
multiplied by vehicle of drug you have equals
the amount calculated to be given to the patient)
D =desired dose
H =dose you have
V=vehicle you have (tablets or liquids)
A=amount calculated to be given to the patient
Ratio and proportion method

H is the drug on hand (available)
V is the vehicle or drug form (tablet, capsule, liquid)
D is the desired dose (as prescribed)
x is the unknown amount to give, and
:: stands for “as” or “equal to.”

Multiply the means and the extremes. Solve for x; x is the divisor.
Example: Give 500 mg of ampicillin sodium by mouth when the dose on hand
is in capsules containing 250 mg.
500 mg divided by 250 mg multiplied by 1 capsule =2 capsules

Formula method:

Example: Give 375 mg of ampicillin when it is supplied as 250 mg/5mL.

375 mg divided by 250 mg multiplied by 5 mL = 7.5 mL

500


250 1


2


mg
mg

capsule
×=capsules

H: V:: D :x

Means
Extremes

D


H


(^118) CHAPTER 7 Dose Calculations

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