0071483446.pdf

CHAPTER 13 Antimicrobials—Fighting Infection^211

Basic (Natural) Penicillin

Pregnancy Category: B

Protein-Binding: 65%

Half-Life:^1 / 2 hour

Route Dose Time

Penicillin G

PO 200,000–500,000 Every 4 to 6 hours

IV 1–5 mu Every 4 to 6 hours

IM 1.2–2.4 micro units Single dose

Penicillin V (take on empty stomach)

PO 125–500 mg Every 8 hours

Penicillinase-Resistant Penicillin

Pregnancy Category: B

Half-Life:^1 / 2 –1 hour

Route Dose Time

cloxacillin (Tegopen)

Protein-Binding: 90%

PO Every 6 hours

IV 250–500 mg Every 4 to 6 hours

dicloxacillin (Dynapen)

Protein-Binding: 90%

PO 125–250 mg Every 6 hours

methicillin (Staphcillin)

Protein-Binding: 25%–40%

IV 1 g Every 6 hours

IM 1 g Every 4 to 6 hours

nafcillin (Unipen)

Protein-Binding: 90%

PO 250 mg–1 g Every 4 to 6 hours

IV 0.5–1.5 g Every 4 hours

IM 500 mg Every 4 to 6 hours