(^212) CHAPTER 13 Antimicrobials—Fighting Infection
Aminopenicillins (Broad Spectrum) Penicillin
Pregnancy Category: B
Route Dose Time
amoxicillin (Amoxil)
Protein-Binding: 20%
Half-Life: 1–1.3 hours
PO 250–500 mg Every 8 hours
amoxicillin + potassium clavulanate (Augmentin, Clavulin)
Protein-Binding: 25%
Half-Life: 1–1^1 / 2 hours
PO 5000 mg Every 8 hours
ampicillin (Polycillin, Omnipen)
Protein-Binding: 15%–28%
Half-Life: 1–2 hours
PO 250–500 mg Every 6 hours
IV 250–500 mg Every 8 hours
IM 250–500 mg Every 8 hours
ampicillin and sulbactam (Unasyn)
Protein-Binding: 28%–38%
Half-Life: 1–2 hours
IV 1.5–3 g Every 6 hours
IM 1.5–3 g Every 6 hours
bacampicillin (Spectrobid)
Protein-Binding: 17%–20%
Half-Life: 1 hour
PO 499–800 mg Every 12 hours
Penicillinase-Resistant Penicillin(continued)
oxacillin (Prostaphlin)
Protein-Binding: 95%
PO 0.5–1 g Every 4 to 6 hours
IV 250–1 g Every 6 hours
IM 250–1 g Every 4 to 6 hours
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