MISCELLANEOUS ANTIBIOTICS
The following shows other antibiotics that are likely to be prescribed to treat
microbial infections.(^240) CHAPTER 13 Antimicrobials—Fighting Infection
Antibiotic Description
Aztreonam (Azactam) Synthetic bactericidal activity similar to PCN
Use: treats urinary tract, bronchitis, intraabdominal,
gynecologic, and skin infections
Route: IV
Dose: 0.5 to 2g
Time: q8–12 h
Protein-Binding: 56%
Half-Life: 1.7–2.1 h
Pregnancy Category: B
Side Effects: Gastric distress, diarrhea, nausea, vomiting,
hypersensitivity, and thrombophlebitis at the site
of injection
Drug interaction: None
Imipenem-cilastatin Use: treats bone, joint, skin, and soft tissue infections,
(Primaxin IM, Primaxin IV) bacterial endocarditis, intraabdominal bacteria infections,
pneumonia, and gram-+, gram- –aerobic and anerobic
organisms
Route: IV, IM
Dose: IV 250–500 mg q6h for mild infections to
500 mg for moderate to severe infections.
Maximum dose is 50 mg/kg daily
IM 500–750 mg up to a maximum of 1500 mg/day.
Time: IV q6–8h
IM q12h
Protein-Binding: 20%
Half-Life: 1 h
Pregnancy Category: C
Side Effects: gastric distress, diarrhea, nausea, vomiting,
allergic type reactions, confusion, lightheadedness,
convulsions, and tremor