CHAPTER 98 • THE FEMALE ATHLETE 577
diagnosis of exclusion. Pregnancy is the most common
cause of amenorrhea in sexually active women, and
must be excluded. Other diagnoses to rule out include
polycystic ovarian syndrome (PCOS), Asherman’s
syndrome, and thyroid or pituitary abnormalities.
- If a woman over the age of 30 is presenting with sec-
ondary amenorrhea, other etiologies to be considered
are premature ovarian failure, endometrial hyperpla-
sia, and carcinoma.
•Exercise-related amenorrhea is thought to be second-
ary to an energy deficit from an inadequate caloric
intake in relationship to energy expenditure. It is
thought that girls or women who are having menstrual
irregularities secondary to an energy deficit are at risk
of decreased bone mineral density (BMD) as well.
The primary treatment that is recommended at this
time is correcting the energy deficit by increasing
caloric intake to the point that there is a spontaneous
return of menses. This has been associated with an
increase in bone mass as well.
OSTEOPOROSIS
- Osteoporosis is characterized by microarchitectural
deterioration of bone tissue leading to enhanced
skeletal fragility, low bone mass, and an increased risk
for fracture.
FIG. 98-1 Laboratory Evaluation of Amenorrhea. Source: Adapted from: Fieseler CM. Special con-
siderations for the female runner. Journal of Back and Musculoskeletal Rehabilitation.Vol. 6. 1996.