Introductory Biostatistics

(Chris Devlin) #1

marginal probabilities above, calculated separately forXandY, are summa-
rized and displayed in Table 3.2. Observe that the four cell probabilities add
to unity [i.e., one of the four eventsðX¼þ;Y¼þÞorðX¼þ;Y¼Þor
ðX¼;Y¼þÞor ðX¼;Y¼Þis certain to be true for a randomly
selected individual from the population]. Also note that the joint probabilities
in each row (or column) add up to themarginalorunivariate probabilityat the
margin of that row (or column). For example,


PrðX¼þ;Y¼þÞþPrðX¼;Y¼þÞ¼PrðY¼þÞ
¼ 0 : 015

We now consider a third type of probability. For example, thesensitivityis
expressible as


sensitivity¼

154


379


¼ 0 : 406


calculated for the eventðX¼þÞusing the subpopulation havingðY¼þÞ.
That is, of the total number of 379 persons with cancer, the proportion
with a positive test result, is 0.406 or 40.6%. This number, denoted by
PrðX¼þjY¼þÞ, is called aconditional probability(Y¼þbeing the condi-
tion) and is related to the other two types of probability:


PrðX¼þjY¼þÞ¼

PrðX¼þ;Y¼þÞ
PrðY¼þÞ

or


PrðX¼þ;Y¼þÞ¼PrðX¼þjY¼þÞPrðY¼þÞ

Clearly, we want to distinguish this conditional probability,
PrðX¼þjY¼þÞ, from the marginal probability,PrðX¼þÞ. If they are
equal,


PrðX¼þjY¼þÞ¼PrðX¼þÞ

TABLE 3.2


X

Y þTotal


þ 0.006 0.009 0.015
 0.015 0.970 0.985


Total 0.021 0.979 1.00


PROBABILITY 113
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