Introductory Biostatistics

(Chris Devlin) #1

0.05 level; there is enough evidence to support the hypothesis ofdi¤erentmean
zinc concentrations (two-sided alternative).
Note: An SAS program would include these instructions:


DATA;


INPUT BZINC SZINC;


DIFF = BZINC - SZINC;


DATALINES;


.430 .415


.266 .238


.567 .390


.531 .410


.707 .605


.716 .609;


PROC MEANS N MEAN STDERR T PRT;


for which we’ll get sample size (N), sample mean (MEAN), standard error
(STDERR),tstatistic (T), andpvalue (PRT).


Example 7.3 The systolic blood pressures ofn¼12 women between the ages
of 20 and 35 were measured before and after administration of a newly devel-
oped oral contraceptive. Data are shown in Table 7.2 (the di¤erence is after–
before). The necessary summarized figures are


TABLE 7.2


Systolic Blood
Pressure (mmHg)

Subject Before After


Di¤erence,
di di^2
1 122 127 5 25
2 126 128 2 4
3 132 140 8 64
4 120 119  11
5 142 145 3 9
6 130 130 0 0
7 142 148 6 36
8 137 135  24
9 128 129 1 1
10 132 137 5 25
11 128 128 0 0
12 129 133 4 16


31 185

ANALYSIS OF PAIR-MATCHED DATA 251
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