100 QUESTIONS IN CARDIOLOGY

(Michael S) #1

41 When should we operate to relieve mitral


regurgitation?


Tom Treasure


There are three circumstances when surgery is required for mitral

regurgitation:

1 To save life in the acute case


Sudden mitral regurgitation following rupture of degenerative

chordae tendineae, papillary muscle rupture, or endocarditis may

be very poorly tolerated. The surgeon may be presented with a

patient in pulmonary oedema, even ventilated, and then an oper-

ation may be the only way to save life.

2 The symptomatic patient with chronic mitral regurgitation


Surgical relief of regurgitant valve lesions can bring dramatic

relief. The decision is not always easy but a sensible appraisal

of the risks and benefits is what is needed. If there is a

tolerably good ventricle, and substantial regurgitation to

correct, then the benefits are likely to outweigh the risks. The

degree of left venticular dilatation to be tolerated before

surgery is required has reduced. In general, it is now suggested

that a left ventricular end-systolic dimension (LVESD) of

4.5cm is a sensible threshold for “perhaps not waiting any

longer”.

3 Mitral regurgitation and the dilated ventricle


The third scenario is the most difficult. Some patients seem to

tolerate mitral regurgitation quite well with a large ventricle

ejecting partly into a large, relatively low pressure left atrium.

The left ventricle may not be as good as it appears because the

high ejection fraction is into low afterload. If you continue to wait

the risks only get higher. Any increasing tendency in LVESD is

ominous and the onset or progression of symptoms should

prompt operation to protect the future.
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