60 What are the survival figures for heart and
heart-lung transplantation?
Brendan Madden
In the International Registry for Heart and Lung Transplantation,
the one year actuarial survival following cardiac transplantation
is approximately 80%. Thereafter there is an annual attrition rate
of 2 to 4% so that five year actuarial survival and ten year actuarial
survival is approximately 65% and 50% respectively. One and
three year actuarial survival following heart-lung and bilateral
lung transplantation is approximately 70% and 50% respectively
and approximately 80% and 60% respectively following single
lung transplantation. Most survivors demonstrate a marked
improvement in quality of life. Lung function increases rapidly
following surgery and forced expiratory volume in one second
and forced vital capacity are usually in excess of 70% by the end
of the third postoperative month. Results of living related lobar
transplantation are similar to those for heart-lung and bilateral
lung transplantation.
The most serious late complication following cardiac trans-
plantation is transplant associated coronary artery disease and
following pulmonary transplantation is obliterative bronchiolitis.
FFuurrtthheerr rreeaaddiinngg
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