Biology of Disease

individuals having the same ‘set’ of HLA genes is very small, making the pos- sibility of finding ‘good’ transplant matches, oth ...

of match required depends on the organ being transplanted, and is much more stringent for bone marrow transplants than for solid ...

it is probable that the recipient already has antibodies against graft antigens and the donor is unlikely to be a suitable match ...

The second generation of immunosuppressive treatments target T lym- phocytes rather than B cells. These included the use of anti ...

6.14 Hemopoietic Stem Cell Transplantation The transplantation of hemopoietic stem cells is used to correct some immu- nodeficie ...

Peripheral Blood Stem Cell Transplantation Peripheral blood stem cell transplantation (PBSCT) is the most common form of SCT. Co ...

Post-transplant support Patients who have just undergone BMT or PBSCT transplantation are highly susceptible to infections. If t ...

presence of antibodies in pregnant women that might cause problems for a developing fetus. Transplantation of solid tissue has p ...

X]VeiZg+/ TRANSFUSION AND TRANSPLANTATION &*+ W^dad\nd[Y^hZVhZ Daniels, GL, Cartron, JP, Fletcher, A, Garratty, G, Henry, ...

&*, X]VeiZg,/ DISORDERS OF THE ENDOCRINE SYSTEM OBJECTIVES After studying this chapter you should be able to: N list the di ...

X]VeiZg,/ DISORDERS OF THE ENDOCRINE SYSTEM &*- W^dad\nd[Y^hZVhZ Anterior pituitary gland Posterior pituitary gland Thyro ...

7.2 Hormone Production Amine hormones include adrenaline, noradrenaline (also called epinephrine and norepinephrine respectively ...

X]VeiZg,/ DISORDERS OF THE ENDOCRINE SYSTEM &+% W^dad\nd[Y^hZVhZ The pineal gland or body is an appendage of the posterio ...

HORMONE PRODUCTION CZhhVg6]bZY!BVjgZZc9Vlhdc!8]g^hHb^i]:YLddY &+& Figure 7.5 The synthesis of melatonin. BOX 7. ...

number of factors control hormone production by the endocrine glands. The secretion of pituitary hormones is under the influence ...

MECHANISMS OF HORMONAL ACTION CZhhVg6]bZY!BVjgZZc9Vlhdc!8]g^hHb^i]:YLddY &+( Figure 7.7 Examples of hormone seconda ...

Margin Note 7.1 G proteins G proteins are so called because they bind the guanyl nucleotides, GDP and GTP. They are a diverse gr ...

THE PITUITARY GLAND CZhhVg6]bZY!BVjgZZc9Vlhdc!8]g^hHb^i]:YLddY &+* Figure 7.10 Mechanism of action of a hormone tha ...

X]VeiZg,/ DISORDERS OF THE ENDOCRINE SYSTEM &++ W^dad\nd[Y^hZVhZ Figure 7.11 Overview of the causes of endocrine disorder ...

THE PITUITARY GLAND CZhhVg6]bZY!BVjgZZc9Vlhdc!8]g^hHb^i]:YLddY &+, Growth hormone acts on general body tissues to p ...