Biology of Disease

the urine. This property is exploited in the xylose absorption test to assess the malabsorption of carbohydrates. The patient fa ...

DISORDERS OF THE GIT AND ACCESSORY ORGANS CZhhVg6]bZY!BVjgZZc9Vlhdc!8]g^hHb^i]:YLddY (%. BOX 11.5 Food allergies A food ...

X]VeiZg&&/ DISORDERS OF THE GASTROINTESTINAL TRACT, PANCREAS, LIVER AND GALL BLADDER (&% W^dad\nd[Y^hZVhZ BOX 11. ...

Crohn’s disease is a chronic inflammation, usually of the ileum, although it can affect any part of the GIT. The inflammation te ...

X]VeiZg&&/ DISORDERS OF THE GASTROINTESTINAL TRACT, PANCREAS, LIVER AND GALL BLADDER (&' W^dad\nd[Y^hZVhZ Mark, a ...

c) oral glucose tolerance test; d) fluorescein dilaurate test; e) xylose absorption test. Qiuyu, a 32-year-old from China, ente ...

McKevith, B and Theobald, H (2005) Common food allergies. Nurs. Stand.19: 39–42. Pearson, C (2004) Inflammatory bowel disease. N ...

(&* X]VeiZg&'/ TOXICOLOGY 12.1 Introduction The human body must be prepared for a daily onslaught of thousands of chemi ...

would not normally occur. An example would be a compound produced by a plant and ingested as food. Equally, it might be a compou ...

However, the response is dose dependent and, indeed, a dose–response relationship exists between the concentration of drug in th ...

X]VeiZg&'/ TOXICOLOGY W^dad\nd[Y^hZVhZ X]VeiZg&'/ TOXICOLOGY (&- W^dad\nd[Y^hZVhZ 12.3 Physiological Detoxific ...

PHYSIOLOGICAL DETOXIFICATION MECHANISMS CZhhVg6]bZY!BVjgZZc9Vlhdc!8]g^hHb^i]:YLddY (&. Blood flow Hepatocyte Bile c ...

glucuronyl transferase R-OH + UDP-glucuronate R-O-glucuronate + UDP sulfotransferase R-OH + PAPS R-O-SO 3 – + PAP The increased ...

12.4 Symptomatic Poisoning In the symptomatic patient, the diagnosis of poisoning is usually made on the basis of clinical findi ...

metabolized by conjugation with glutathione in hepatocytes to produce a nontoxic mercapturic acid. Glutathione is a tripeptide c ...

COMMON POISONS CZhhVg6]bZY!BVjgZZc9Vlhdc!8]g^hHb^i]:YLddY ('( Figure 12.7 An overview of the detoxification and toxic e ...

Stage Duration / h Clinical features I 0.5–24 loss of appetite and anorexia (Chapter 10), nausea and vomiting, general malaise, ...

activities of liver transaminases and measuring serum bilirubin to monitor liver functions (Chapter 11) and determining serum cr ...

hypoglycemia and the catabolism of lipids producing ketone bodies (Chapter 7). Salicylate also inhibits enzymes of the TCA cycle ...

death can occur in children under 18 months from as little as 300 mg. Signs of salicylate toxicity occur when concentrations are ...