Biology of Disease

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  1. Barry, a 55-year-old, was admitted to hospital with severe chest pain,
    which had been present for the past 30 min. He had a previous history
    of angina. Which serum markers should be measured for this patient
    on admission?

  2. If a patient is found to have high VLDL levels in the blood, what
    change in diet could help to lower the concentration?

  3. Suggest why chylomicrons are not taken up by LDL receptors.


Further Reading


Chalela, JA, Merino, JG and Warach, S (2004) Update on stroke. Curr. Opin.
Neurol.17: 447–451.

Chilton, RJ (2004) Pathophysiology of coronary heart disease: a brief review.
J. Am. Osteopath Assoc.104: S5–S8.

Choy, PC, Siow, YL and Mymin, DOK (2004) Lipids and atherosclerosis.
Biochem. Cell Biol. 82: 212–214.

Fox, KF (2005) investigation and management of chest pain. Heart91: 105–
110.

Nicholas, M (2004) Heart failure: pathophysiology, treatment and nursing
care. Nursing Stand.19: 46–51.

Page, RL (2004) Clinical practice. Newly diagnosed atrial fibrillation. N. Engl.
J. Med.351: 2408–2416.

Rullan, F and Sigal, LH (2001) Rheumatic fever. Curr. Rheumatol. Rep.3:
445–452.

Scott, J (2004) Pathophysiology and biochemistry of cardiovascular disease.
Curr. Opin. Genet. Dev. 14: 271–279.

Torney, WT (1996) The diagnosis and management of acute myocardial
infarction – a role for biochemical markers? Ann. Clin. Biochem.33: 477–481.

Yee, CA (2005) Endocarditis: the infected heart. Nursing Manage.36: 25–30.

Useful web sites:


‘Target Heart Diseases’ is a free booklet produced by the Association of
the British Pharmaceutical Industry (ABPI) copies of which are available
from the ABPI, 12 Whitehall, London SW1A 2DY or from their website:
http://www.abpi.org.uk

Cox, D and Dougall, H (2001) What’s so difficult about ECGs – a bundle of
what? – a series of articles for medical students about understanding ECGs,
available on http://www.studentbmj.com

X]VeiZg&)/ DISORDERS OF THE CARDIOVASCULAR SYSTEM


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