X]VeiZg&+/ MEMBRANE, ORGANELLE AND CYTOSKELETAL DISORDERS
)*' W^dad\nd[Y^hZVhZ
X]VeiZg&+/ MEMBRANE, ORGANELLE AND CYTOSKELETAL DISORDERS
W^dad\nd[Y^hZVhZ
Recycling of
adapter and
import receptor
proteins
Cargo
Ran GDP
Ran GTP
GDP
GDP
GTP
GTP
GTP
GTP
Adapter
protein
Import
receptor
CARGO IN
CYTOPLASM
CARGO IN
NUCLEOPLASM
Figure 16.2 A highly simplified outline of the nucleocytoplasmic transport of a protein. Thin continuous arrows
represent the formation and dissociation of protein complexes and the thick arrows their transport. The thin broken
arrows indicate the recycling of the adapter and import receptor proteins.See text for details.