Biology of Disease

5. a) IgG; b) IgG; c) IgA, d) IgE; e) IgM


6. MHC encoded Class 1 proteins are concerned largely with defense
   against viruses. Erythrocytes are not susceptible to viral attack because
   they are anucleated and therefore do not have the genetic machinery
   to support viral replication.

CHAPTER 5

1. (c)


2. (a) False

(b) True

(c) True

(d) False

(e) True

3. 
   

   (b)

   
   


4. 
   

   By removing self-reactive cells during fetal development;
   by keeping immunogens away from the immune system;
   by the production of regulatory cells.

   
   


5. 
   

Selective IgA deficiency may be asymptomatic

Farmer’s lung is caused by immune complexes

Chediak Higashi disease affects melanocytes

Anaphylactic shock is due to IgE

Delayed hypersensitivity is caused by T lymphocytes

CHAPTER 6

1. a, c, and e


2. b (because MHC I proteins are found on all cells, including antigen
   presenting cells) and e; c is untrue because complement is a set of
   proteins not a single one.


3. All except c. A donor who is pregnant may continue to donate blood
   after her pregnancy. All the others would be precluded from donating
   blood.


4. Previous transplant; previous transfusion with whole blood or blood/
   blood product with residual leukocytes; previous pregnancies if
   female.


5. It is technically much easier to obtain PBSCT by leukapheresis than
   it is to obtain bone marrow and the donor does not have to be
   anesthetized.

CHAPTER 7

1. d


2. a


3. b


4. d


5. d

CHAPTER 7

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